Literature DB >> 17468445

The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study.

L Roccatagliata1, Ma Rocca, P Valsasina, L Bonzano, Mp Sormani, R Saccardi, Gl Mancardi, M Filippi.   

Abstract

Using MRI, we measured disease activity and brain atrophy in nine multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT) for a mean follow up of 63 months. We show that AHSCT is associated to a longlasting suppression of inflammation and to a marked decrease of the rate of brain atrophy after the second year following treatment.

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Year:  2007        PMID: 17468445     DOI: 10.1177/1352458507076982

Source DB:  PubMed          Journal:  Mult Scler        ISSN: 1352-4585            Impact factor:   6.312


  16 in total

1.  Cyclophosphamide in multiple sclerosis: scientific rationale, history and novel treatment paradigms.

Authors:  Amer Awad; Olaf Stüve
Journal:  Ther Adv Neurol Disord       Date:  2009-11       Impact factor: 6.570

2.  Multiple sclerosis: Hematopoietic stem cell transplantation: hope and hype.

Authors:  Martin Stangel
Journal:  Nat Rev Neurol       Date:  2009-06       Impact factor: 42.937

Review 3.  [Stem cell therapy in multiple sclerosis: a clinical update].

Authors:  S Schippling; R Martin
Journal:  Z Rheumatol       Date:  2009-05       Impact factor: 1.372

Review 4.  MRI in multiple sclerosis: what's inside the toolbox?

Authors:  Mohit Neema; James Stankiewicz; Ashish Arora; Zachary D Guss; Rohit Bakshi
Journal:  Neurotherapeutics       Date:  2007-10       Impact factor: 7.620

Review 5.  Aggressive multiple sclerosis: proposed definition and treatment algorithm.

Authors:  Carolina A Rush; Heather J MacLean; Mark S Freedman
Journal:  Nat Rev Neurol       Date:  2015-06-02       Impact factor: 42.937

Review 6.  Emerging therapies for multiple sclerosis.

Authors:  Paolo A Muraro; Bibiana Bielekova
Journal:  Neurotherapeutics       Date:  2007-10       Impact factor: 7.620

Review 7.  Preclinical assessment of stem cell therapies for neurological diseases.

Authors:  Valerie L Joers; Marina E Emborg
Journal:  ILAR J       Date:  2009

Review 8.  The place of conventional MRI and newly emerging MRI techniques in monitoring different aspects of treatment outcome.

Authors:  Robert Zivadinov; Milena Stosic; Jennifer L Cox; Deepa P Ramasamy; Michael G Dwyer
Journal:  J Neurol       Date:  2008-03       Impact factor: 4.849

Review 9.  Autologous hematopoietic stem cell transplantation in multiple sclerosis: 20 years of experience.

Authors:  Daniela Currò; Gianluigi Mancardi
Journal:  Neurol Sci       Date:  2016-04-12       Impact factor: 3.307

Review 10.  Stem cell transplantation in multiple sclerosis.

Authors:  Sven Schippling; Christoph Heesen; Axel Zander; Roland Martin
Journal:  J Neurol       Date:  2008-12       Impact factor: 4.849

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