Literature DB >> 17468032

Acute promyelocytic leukemia: new issues on pathogenesis and treatment response.

Dominique Vitoux1, Rihab Nasr, Hugues de The.   

Abstract

Pathogenesis of acute promyelocytic leukemia appears to be one of the best understood among human malignancies. The ability of retinoic acid (RA) and arsenic trioxide to directly target the oncogenic promyelocytic leukemia-retinoic receptor A (PML-RARA) fusion protein also made this disease the first model for oncogene-targeted therapies. A set of recent data has significantly increased the complexity of our view of acute promyelocytic leukemia pathogenesis, as well as of therapeutic response. This review summarizes and discusses these findings, which yield novels questions and models.

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Year:  2007        PMID： 17468032     DOI： 10.1016/j.biocel.2007.01.028

Source DB:  PubMed          Journal:  Int J Biochem Cell Biol        ISSN： 1357-2725            Impact factor:   5.085


  9 in total

1.  Multiple cytochrome P-450 genes are concomitantly regulated by vitamin A under steady-state conditions and by retinoic acid during hepatic first-pass metabolism.

Authors:  A Catharine Ross; Christopher J Cifelli; Reza Zolfaghari; Nan-Qian Li
Journal:  Physiol Genomics       Date:  2010-11-02       Impact factor: 3.107

2.  Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination.

Authors:  Percy Luk Yeung; Natalia G Denissova; Cara Nasello; Zhanna Hakhverdyan; J Don Chen; Mark A Brenneman
Journal:  J Cell Biochem       Date:  2012-05       Impact factor: 4.429

Review 3.  Vitamin A and retinoic acid in the regulation of B-cell development and antibody production.

Authors:  A Catharine Ross; Qiuyan Chen; Yifan Ma
Journal:  Vitam Horm       Date:  2011       Impact factor: 3.421

4.  High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients.

Authors:  Zheng Wang; Lijun Wen; Xiao Ma; Zijun Chen; Yunhui Yu; Jian Zhu; Yanping Wang; Zhenming Liu; Haiyan Liu; Depei Wu; Dapeng Zhou; Yunsen Li
Journal:  Glycobiology       Date:  2012-03-11       Impact factor: 4.313

5.  The roles of bioactive sphingolipids in resveratrol-induced apoptosis in HL60: acute myeloid leukemia cells.

Authors:  Zeynep Cakir; Guray Saydam; Fahri Sahin; Yusuf Baran
Journal:  J Cancer Res Clin Oncol       Date:  2010-04-18       Impact factor: 4.553

6.  A coordinated phosphorylation cascade initiated by p38MAPK/MSK1 directs RARalpha to target promoters.

Authors:  Nathalie Bruck; Dominique Vitoux; Christine Ferry; Vanessa Duong; Annie Bauer; Hughes de Thé; Cécile Rochette-Egly
Journal:  EMBO J       Date:  2008-12-11       Impact factor: 11.598

7.  In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML.

Authors:  Anmaar M Abdul-Nabi; Enas R Yassin; Nobish Varghese; Hrishikesh Deshmukh; Nabeel R Yaseen
Journal:  PLoS One       Date:  2010-08-27       Impact factor: 3.240

Review 8.  Role of Nuclear Receptors in Central Nervous System Development and Associated Diseases.

Authors:  Ana Maria Olivares; Oscar Andrés Moreno-Ramos; Neena B Haider
Journal:  J Exp Neurosci       Date:  2016-05-05

Review 9.  Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs).

Authors:  Cécile Rochette-Egly; Pierre Germain
Journal:  Nucl Recept Signal       Date:  2009-05-08
  9 in total

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