| Literature DB >> 17467987 |
Frédéric Denonne1, Sophie Binet, Maggi Burton, Philippe Collart, Alan Dipesa, Tanmoy Ganguly, Alexander Giannaras, Seema Kumar, Timothy Lewis, Florence Maounis, Jean-Marie Nicolas, Tamsin Mansley, Patrick Pasau, Dorin Preda, Karin Stebbins, Alexander Volosov, Dong Zou.
Abstract
The synthesis and in vitro binding of several new arginine-containing C3aR ligands are reported. DMPK properties and functional activities of selected compounds have been evaluated. One compound is shown to be active in an in vivo model of airway inflammation after aerosol administration.Entities:
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Year: 2007 PMID： 17467987 DOI： 10.1016/j.bmcl.2007.04.022
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823