| Literature DB >> 17467258 |
Abstract
Recent studies show that genes far apart on the same chromosome or even on different chromosomes can come together in the nuclear space. It has been hypothesized that functionally related genes 'kiss' at transcription factories to coordinate their expression. Novel high-throughput methods, such as 4C technology, that study DNA interactions in an unbiased manner should uncover the generality of this romantic concept of nuclear architecture.Mesh：
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Year: 2007 PMID： 17467258 DOI： 10.1016/j.ceb.2007.04.004
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382