Literature DB >> 17466617

p53 and NF-kappaB crosstalk: IKKalpha tips the balance.

Vinay Tergaonkar1, Neil D Perkins.   

Abstract

Crosstalk between the NF-kappaB and p53 transcription factors can play a pivotal role in determining the cellular response to stress; in a recent issue of Molecular Cell, Huang et al. (2007) show that IkappaB kinase alpha (IKKalpha) can determine which pathway is dominant.

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Year:  2007        PMID： 17466617     DOI： 10.1016/j.molcel.2007.04.006

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  42 in total

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8.  MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma.

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10.  Elucidation of functional consequences of signalling pathway interactions.

Authors:  Adaoha E C Ihekwaba; Phuong T Nguyen; Corrado Priami
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