BACKGROUND: Mesenchymal vulvar tumors are rare, and a benign lipoblastomalike tumor may be confused with malignancy. CASE: A 15-year-old patient consulted for a right labium tumefaction measuring 15 cm. After excision, histologic examination revealed a well-circumscribed and lobulated tumor. The lobules were composed of slender spindle cells showing slightly eosinophilic cytoplasm with indistinct boundaries, uniform nuclei with finely granular chromatin and no nucleoli. Scattered Signet-ring-type lipoblasts were observed. The background was myxoid, with a "chickenwire" capillary vascular network mimicking a myxoid liposarcoma. No mitotic figures, necrosis or pleomorphism was noted. CONCLUSION: This mesenchymal tumor had adipocytic differentiation and no patent sign of malignancy, akin to infantile lipoblastoma. Because of the benign behavior of this tumor, complete excision without radiation is recommended.
BACKGROUND: Mesenchymal vulvar tumors are rare, and a benign lipoblastomalike tumor may be confused with malignancy. CASE: A 15-year-old patient consulted for a right labium tumefaction measuring 15 cm. After excision, histologic examination revealed a well-circumscribed and lobulated tumor. The lobules were composed of slender spindle cells showing slightly eosinophilic cytoplasm with indistinct boundaries, uniform nuclei with finely granular chromatin and no nucleoli. Scattered Signet-ring-type lipoblasts were observed. The background was myxoid, with a "chickenwire" capillary vascular network mimicking a myxoid liposarcoma. No mitotic figures, necrosis or pleomorphism was noted. CONCLUSION: This mesenchymal tumor had adipocytic differentiation and no patent sign of malignancy, akin to infantile lipoblastoma. Because of the benign behavior of this tumor, complete excision without radiation is recommended.
Authors: Marco Gambarotti; Kivilcim E Erdogan; Alberto Righi; Stefania Benini; Maria Rosaria Raspollini; Augusto Delle Rose; Giovanna Magagnoli; Marta Sbaraglia; Angelo P Dei Tos Journal: Virchows Arch Date: 2020-07-02 Impact factor: 4.064