Literature DB >> 17464592

Surgical staging, treatment, and follow-up of borderline tumors in different hospital categories: a prospective nationwide survey in Finland.

Salla Kumpulainen1, Tapio Kuoppala, Arto Leminen, Marja Komulainen, Ulla Puistola, Risto Sankila, Juha Mäkinen, Seija Grénman.   

Abstract

BACKGROUND: Surgical treatment and staging of ovarian borderline tumors have been reported to be often suboptimal and differ considerably. We evaluated the extent of surgical treatment of these tumors in different hospital categories.
MATERIAL AND METHODS: A prospective survey performed in 1999 included 65 patients operated on for borderline ovarian tumors and covered 78% of such patients reported to the Finnish Cancer Registry. Detailed information of demographic data and surgical treatment was reported by the responsible physicians using a special questionnaire after confirmation of histopathology.
RESULTS: Fifty-eight patients (89%) had stage I tumor, only two patients (3%) had stage II disease and five patients (8%) had stage III disease with peritoneal implants. The majority of the patients underwent bilateral salpingo-oophorectomy (66%) and hysterectomy (58%). Unilateral salpingo-oophorectomy was performed for 21 (32%) and omentectomy for 22 (34%) patients. Ten out of the 16 women under 40 years of age had fertility-sparing surgery. Peritoneal biopsies were taken in 16 (25%) women and lymphadenectomy was performed for 9 (14%) patients with clinical suspicion of invasive ovarian carcinoma. Frozen section was taken in half of the patients and the histology remained the same in 72% of the final pathology reports. No clear differences of the extent of surgical treatment were detected between different hospital categories. Overall cumulative 5-year relative survival rate was 96%.
CONCLUSIONS: Bilateral salpingo-oophorectomy and hysterectomy was performed for the majority of patients with borderline ovarian tumor. More attention should be paid to adequate staging of borderline tumors in all hospital categories.

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Year:  2007        PMID: 17464592     DOI: 10.1080/00016340701284707

Source DB:  PubMed          Journal:  Acta Obstet Gynecol Scand        ISSN: 0001-6349            Impact factor:   3.636


  6 in total

1.  Accuracy of Intraoperative Frozen Section Diagnosis of Borderline Ovarian Tumors by Hospital Type.

Authors:  Jaimin S Shah; Michael Mackelvie; David M Gershenson; Preetha Ramalingam; Marylee M Kott; Jubilee Brown; Polly Gauthier; Elizabeth Nugent; Lois M Ramondetta; Michael Frumovitz
Journal:  J Minim Invasive Gynecol       Date:  2018-04-19       Impact factor: 4.137

2.  Borderline ovarian tumors and diagnostic dilemma of intraoperative diagnosis: could preoperative He4 assay and ROMA score assessment increase the frozen section accuracy? A multicenter case-control study.

Authors:  Salvatore Gizzo; Roberto Berretta; Stefania Di Gangi; Maria Guido; Giuliano Carlo Zanni; Ilaria Franceschetti; Michela Quaranta; Mario Plebani; Giovanni Battista Nardelli; Tito Silvio Patrelli
Journal:  Biomed Res Int       Date:  2014-11-05       Impact factor: 3.411

Review 3.  Intraoperative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses.

Authors:  Nithya D G Ratnavelu; Andrew P Brown; Susan Mallett; Rob J P M Scholten; Amit Patel; Christina Founta; Khadra Galaal; Paul Cross; Raj Naik
Journal:  Cochrane Database Syst Rev       Date:  2016-03-01

4.  Histologic distribution of borderline ovarian tumors worldwide: a systematic review.

Authors:  Taejong Song; Yoo-Young Lee; Chel Hun Choi; Tae-Joong Kim; Jeong-Won Lee; Duk-Soo Bae; Byoung-Gie Kim
Journal:  J Gynecol Oncol       Date:  2013-01-08       Impact factor: 4.401

5.  Clinical management of borderline tumours of the ovary: results of a multicentre survey of 323 clinics in Germany.

Authors:  A Coumbos; J Sehouli; R Chekerov; D Schaedel; G Oskay-Oezcelik; W Lichtenegger; W Kuehn
Journal:  Br J Cancer       Date:  2009-05-12       Impact factor: 7.640

6.  Epithelial ovarian cancer subtypes attributable to smoking in the Norwegian Women and Cancer Study, 2012.

Authors:  Idlir Licaj; Marko Lukic; Mie Jareid; Eiliv Lund; Tonje Braaten; Inger Torhild Gram
Journal:  Cancer Med       Date:  2016-01-14       Impact factor: 4.452

  6 in total

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