Literature DB >> 17462568

A direct inhibitor of HMGB1 cytokine.

Jean-Philippe Girard1.   

Abstract

HMGB1 and the recently described interleukin-33 (IL-33) are abundant chromatin-associated nuclear factors with potent proinflammatory cytokine activities. In this issue of Chemistry & Biology, Mollica et al. [1] report the identification of the first direct small-molecule inhibitor of HMGB1.

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Year:  2007        PMID: 17462568     DOI: 10.1016/j.chembiol.2007.04.001

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  19 in total

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3.  PGE2 receptor agonist misoprostol protects brain against intracerebral hemorrhage in mice.

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Review 4.  Acute kidney injury: a conspiracy of Toll-like receptor 4 on endothelia, leukocytes, and tubules.

Authors:  Christopher Y Lu; Pamela D Winterberg; Jianlin Chen; John R Hartono
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5.  Surfactant protein-A inhibits mycoplasma-induced dendritic cell maturation through regulation of HMGB-1 cytokine activity.

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6.  High mobility group box1 protein is involved in acute inflammation induced by Clostridium difficile toxin A.

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Review 7.  Damage-associated molecular patterns in the pathogenesis of osteoarthritis: potentially novel therapeutic targets.

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8.  Role of ROS and HMGB1 in contact allergen-induced IL-18 production in human keratinocytes.

Authors:  Valentina Galbiati; Angela Papale; Corrado L Galli; Marina Marinovich; Emanuela Corsini
Journal:  J Invest Dermatol       Date:  2014-04-29       Impact factor: 8.551

9.  Glycyrrhizin ameliorates experimental colitis through attenuating interleukin-17-producing T cell responses via regulating antigen-presenting cells.

Authors:  Xiangyu Chen; Dai Fang; Lingyun Li; Liyong Chen; Qirui Li; Feili Gong; Min Fang
Journal:  Immunol Res       Date:  2017-06       Impact factor: 2.829

Review 10.  HMGB1 in hormone-related cancer: a potential therapeutic target.

Authors:  Madhuwanti Srinivasan; Souresh Banerjee; Allison Palmer; Guoxing Zheng; Aoshuang Chen; Maarten C Bosland; André Kajdacsy-Balla; Ramaswamy Kalyanasundaram; Gnanasekar Munirathinam
Journal:  Horm Cancer       Date:  2014-04-10       Impact factor: 3.869

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