Literature DB >> 17462055

Development and descent of the testis in relation to cryptorchidism.

Helena E Virtanen1, Dina Cortes, Ewa Rajpert-De Meyts, E Martin Ritzén, Agneta Nordenskjöld, Niels E Skakkebaek, Jorma Toppari.   

Abstract

UNLABELLED: The testis descends in two phases. Animal studies suggest, that the transabdominal descent of the testis depends on the insulin-like hormone 3 (INSL3). Androgens are important in the inguinoscrotal testicular descent in animals and humans. In general, the cause of cryptorchidism is unknown and the aetiology is possibly multifactorial. Histological changes in cryptorchid testes demonstrate disturbed development.
CONCLUSION: Since testicular descent is regulated by testis-derived hormones, cryptorchidism may reflect a functional defect of the testis.

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Year:  2007        PMID： 17462055     DOI： 10.1111/j.1651-2227.2007.00244.x

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN： 0803-5253            Impact factor:   2.299


  14 in total

Review 1.  [Cryptorchidism and fertility].

Authors:  I Rübben
Journal:  Urologe A       Date:  2016-07       Impact factor: 0.639

2.  The timing of surgery for undescended testis - a retrospective multicenter analysis.

Authors:  Georg Hrivatakis; Wolfgang Astfalk; Andreas Schmidt; Andreas Hartwig; Thomas Kugler; Thomas Heim; Axel Clausner; Albrecht Frunder; Harduin Weber; Steffan Loff; Joerg Fuchs; Verena Ellerkamp
Journal:  Dtsch Arztebl Int       Date:  2014-09-26       Impact factor: 5.594

3.  Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism.

Authors:  Michelle Welsh; Philippa T K Saunders; Mark Fisken; Hayley M Scott; Gary R Hutchison; Lee B Smith; Richard M Sharpe
Journal:  J Clin Invest       Date:  2008-04       Impact factor: 14.808

Review 4.  The undescended testis: diagnosis, treatment and long-term consequences.

Authors:  Michael J Mathers; Herbert Sperling; Herbert Rübben; Stephan Roth
Journal:  Dtsch Arztebl Int       Date:  2009-08-14       Impact factor: 5.594

Review 5.  Cholesterol Contributes to Male Sex Differentiation Through Its Developmental Role in Androgen Synthesis and Hedgehog Signaling.

Authors:  Anbarasi Kothandapani; Colin R Jefcoate; Joan S Jorgensen
Journal:  Endocrinology       Date:  2021-07-01       Impact factor: 4.736

6.  Serum AMH concentration as a marker evaluating gonadal function in boys operated on for unilateral cryptorchidism between 1st and 4th year of life.

Authors:  Ewa Matuszczak; Adam Hermanowicz; Wojciech Debek; Marzanna Oksiuta; Ewa Dzienis-Koronkiewicz; Beata Zelazowska-Rutkowska
Journal:  Endocrine       Date:  2011-10-29       Impact factor: 3.633

7.  The risk of cryptorchidism among sons of women working in horticulture in Denmark: a cohort study.

Authors:  Pernille Gabel; Morten Søndergaard Jensen; Helle Raun Andersen; Jesper Baelum; Ane Marie Thulstrup; Jens Peter Bonde; Gunnar Toft
Journal:  Environ Health       Date:  2011-11-14       Impact factor: 5.984

8.  Management of cryptorchidism: a survey of clinical practice in Italy.

Authors:  Federico Marchetti; Jenny Bua; Gianluca Tornese; Gianni Piras; Giacomo Toffol; Luca Ronfani
Journal:  BMC Pediatr       Date:  2012-01-10       Impact factor: 2.125

9.  Age at presentation of undescended testicles: a single-center study in Saudi Arabia.

Authors:  Ossamah S Alsowayan; Jumanah H Basalelah; Abdullah M Alzahrani; Abdulaziz M Alshaibani; Nasser S Alalyani; Turki A Alsubiani; Maha Khalid AlMadi
Journal:  Ann Saudi Med       Date:  2018 Mar-Apr       Impact factor: 1.526

10.  Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy.

Authors:  Helle R Andersen; Ida M Schmidt; Philippe Grandjean; Tina K Jensen; Esben Budtz-Jørgensen; Mia B Kjaerstad; Jesper Baelum; Jesper B Nielsen; Niels E Skakkebaek; Katharina M Main
Journal:  Environ Health Perspect       Date:  2008-04       Impact factor: 9.031
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