| Literature DB >> 17459739 |
Gunnar M Buyse1, Nathalie Goemans, Erik Henricson, Alejandro Jara, Marleen van den Hauwe, Robert Leshner, Julaine M Florence, Jill E Mayhew, Diana M Escolar.
Abstract
The authors report a pilot open-label two-center therapeutic trial of oxatomide in 14 steroid-naive DMD boys aged 5-10 years. Comparison of linear evolutions between 3 months medication-free lead-in periods and 6 months treatment periods showed no significant differences in quantitative (QMT) and manual (MMT) measurements of muscle strength and timed functional tests. A modest mitigation of strength deterioration over time cannot be excluded.Entities:
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Year: 2007 PMID： 17459739 DOI： 10.1016/j.ejpn.2007.02.009
Source DB: PubMed Journal: Eur J Paediatr Neurol ISSN： 1090-3798 Impact factor: 3.140