Literature DB >> 17458842

Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors.

Antonello Mai1, Sergio Valente, Donghang Cheng, Andrea Perrone, Rino Ragno, Silvia Simeoni, Gianluca Sbardella, Gerald Brosch, Angela Nebbioso, Mariarosaria Conte, Lucia Altucci, Mark T Bedford.   

Abstract

Mesh：

Substances：

Year:  2007        PMID： 17458842     DOI： 10.1002/cmdc.200700023

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


× No keyword cloud information.
  19 in total

1.  Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production.

Authors:  Kevin Bonham; Saskia Hemmers; Yeon-Hee Lim; Dawn M Hill; M G Finn; Kerri A Mowen
Journal:  FEBS J       Date:  2010-03-22       Impact factor: 5.542

Review 2.  Minireview: protein arginine methylation of nonhistone proteins in transcriptional regulation.

Authors:  Young-Ho Lee; Michael R Stallcup
Journal:  Mol Endocrinol       Date:  2009-01-22

Review 3.  Protein arginine methylation in parasitic protozoa.

Authors:  John C Fisk; Laurie K Read
Journal:  Eukaryot Cell       Date:  2011-06-17

4.  Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies.

Authors:  Sergio Valente; Veronica Rodriguez; Ciro Mercurio; Paola Vianello; Bruna Saponara; Roberto Cirilli; Giuseppe Ciossani; Donatella Labella; Biagina Marrocco; Giovanni Ruoppolo; Oronza A Botrugno; Paola Dessanti; Saverio Minucci; Andrea Mattevi; Mario Varasi; Antonello Mai
Journal:  ACS Med Chem Lett       Date:  2014-12-08       Impact factor: 4.345

5.  Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity.

Authors:  Donghang Cheng; Sergio Valente; Sabrina Castellano; Gianluca Sbardella; Roberto Di Santo; Roberta Costi; Mark T Bedford; Antonello Mai
Journal:  J Med Chem       Date:  2011-06-13       Impact factor: 7.446

6.  Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.

Authors:  Paolo Mellini; Biagina Marrocco; Diana Borovika; Lucia Polletta; Ilaria Carnevale; Serena Saladini; Giulia Stazi; Clemens Zwergel; Peteris Trapencieris; Elisabetta Ferretti; Marco Tafani; Sergio Valente; Antonello Mai
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-06-05       Impact factor: 6.237

7.  Xenoestrogens regulate the activity of arginine methyltransferases.

Authors:  Donghang Cheng; Mark T Bedford
Journal:  Chembiochem       Date:  2010-12-17       Impact factor: 3.164

8.  Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.

Authors:  Sabrina Castellano; Astrid Spannhoff; Ciro Milite; Fabrizio Dal Piaz; Donghang Cheng; Alessandra Tosco; Monica Viviano; Abdellah Yamani; Agostino Cianciulli; Marina Sala; Vincent Cura; Jean Cavarelli; Ettore Novellino; Antonello Mai; Mark T Bedford; Gianluca Sbardella
Journal:  J Med Chem       Date:  2012-11-02       Impact factor: 7.446

9.  Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.

Authors:  Roberta Ciarapica; Elena Carcarino; Laura Adesso; Maria De Salvo; Giorgia Bracaglia; Pier Paolo Leoncini; Alessandra Dall'agnese; Federica Verginelli; Giuseppe M Milano; Renata Boldrini; Alessandro Inserra; Stefano Stifani; Isabella Screpanti; Victor E Marquez; Sergio Valente; Antonello Mai; Pier Lorenzo Puri; Franco Locatelli; Daniela Palacios; Rossella Rota
Journal:  BMC Cancer       Date:  2014-02-27       Impact factor: 4.430

Review 10.  Six Years (2012-2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2-Pyridone Compounds.

Authors:  Rossella Fioravanti; Giulia Stazi; Clemens Zwergel; Sergio Valente; Antonello Mai
Journal:  Chem Rec       Date:  2018-10-19       Impact factor: 6.771
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.