Literature DB >> 17458441

Jumping to conclusions: a network model predicts schizophrenic patients' performance on a probabilistic reasoning task.

Simon C Moore1, Joselyn L Sellen.   

Abstract

This article extends computational models of schizophrenia that focus on the negative aspects of this syndrome to behavioral biases that are associated with a positive symptom of schizophrenia, namely delusions. The phenomenon studied is the "jump-to-conclusions" style of reasoning that is characterized by delusional patients--in comparison with controls--whereby they make less-informed decisions when an option to collect more decision-specific information is available. Simulations show that these differences can be mimicked by modulating the gain parameter-associated with variations in dopamine level-in a simple network model.

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Year:  2006        PMID: 17458441     DOI: 10.3758/cabn.6.4.261

Source DB:  PubMed          Journal:  Cogn Affect Behav Neurosci        ISSN: 1530-7026            Impact factor:   3.282


  35 in total

Review 1.  Cognitive approaches to delusions: a critical review of theories and evidence.

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Journal:  Br J Clin Psychol       Date:  1999-06

2.  A network model of catecholamine effects: gain, signal-to-noise ratio, and behavior.

Authors:  D Servan-Schreiber; H Printz; J D Cohen
Journal:  Science       Date:  1990-08-24       Impact factor: 47.728

3.  A computational role for dopamine delivery in human decision-making.

Authors:  D M Egelman; C Person; P R Montague
Journal:  J Cogn Neurosci       Date:  1998-09       Impact factor: 3.225

4.  Reasoning biases in delusion-prone individuals.

Authors:  Y M Linney; E R Peters; P Ayton
Journal:  Br J Clin Psychol       Date:  1998-09

5.  Probabilistic reasoning in deluded, depressed and normal subjects: effects of task difficulty and meaningful versus non-meaningful material.

Authors:  H F Young; R P Bentall
Journal:  Psychol Med       Date:  1997-03       Impact factor: 7.723

6.  Naive theories and causal deduction.

Authors:  D D Cummins
Journal:  Mem Cognit       Date:  1995-09

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Authors:  J J Hopfield
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

8.  Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method.

Authors:  A Breier; T P Su; R Saunders; R E Carson; B S Kolachana; A de Bartolomeis; D R Weinberger; N Weisenfeld; A K Malhotra; W C Eckelman; D Pickar
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-18       Impact factor: 11.205

9.  Neural basis of a perceptual decision in the parietal cortex (area LIP) of the rhesus monkey.

Authors:  M N Shadlen; W T Newsome
Journal:  J Neurophysiol       Date:  2001-10       Impact factor: 2.714

Review 10.  Paranoid schizophrenia may be caused by dopamine hyperactivity of CA1 hippocampus.

Authors:  E E Krieckhaus; J W Donahoe; M A Morgan
Journal:  Biol Psychiatry       Date:  1992-03-15       Impact factor: 13.382

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  4 in total

1.  Cognitive behavioral therapy for subjects at ultrahigh risk for developing psychosis: a randomized controlled clinical trial.

Authors:  Mark van der Gaag; Dorien H Nieman; Judith Rietdijk; Sara Dragt; Helga K Ising; Rianne M C Klaassen; Maarten Koeter; Pim Cuijpers; Lex Wunderink; Don H Linszen
Journal:  Schizophr Bull       Date:  2012-09-01       Impact factor: 9.306

Review 2.  Jumping to conclusions in schizophrenia.

Authors:  Simon L Evans; Bruno B Averbeck; Nicholas Furl
Journal:  Neuropsychiatr Dis Treat       Date:  2015-07-01       Impact factor: 2.570

3.  Psychotic Experiences and Overhasty Inferences Are Related to Maladaptive Learning.

Authors:  Heiner Stuke; Hannes Stuke; Veith Andreas Weilnhammer; Katharina Schmack
Journal:  PLoS Comput Biol       Date:  2017-01-20       Impact factor: 4.475

4.  Neural computations mediating one-shot learning in the human brain.

Authors:  Sang Wan Lee; John P O'Doherty; Shinsuke Shimojo
Journal:  PLoS Biol       Date:  2015-04-28       Impact factor: 8.029

  4 in total

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