Literature DB >> 17457656

Propagation of fluctuations in biochemical systems, I: linear SSC networks.

David F Anderson1, Jonathan C Mattingly, H Frederik Nijhout, Michael C Reed.   

Abstract

We investigate the propagation of random fluctuations through biochemical networks in which the number of molecules of each species is large enough so that the concentrations are well modeled by differential equations. We study the effect of network topology on the emergent properties of the reaction system by characterizing the behavior of variance as fluctuations propagate down chains and studying the effect of side chains and feedback loops. We also investigate the asymptotic behavior of the system as one reaction becomes fast relative to the others.

Mesh:

Year:  2007        PMID: 17457656     DOI: 10.1007/s11538-007-9192-2

Source DB:  PubMed          Journal:  Bull Math Biol        ISSN: 0092-8240            Impact factor:   1.758


  5 in total

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