Literature DB >> 17457425

Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine.

Philip A Gale1, Joachim Garric, Mark E Light, Beth A McNally, Bradley D Smith.   

Abstract

Replacement of the central isophthalamide core in a synthetic HCl receptor, with a 2,6-dicarboxamidopyridine, leads to a more preorganised molecular structure that exhibits higher chloride affinity and membrane transport flux.

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Year:  2007        PMID: 17457425      PMCID: PMC2864111          DOI: 10.1039/b703259e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  13 in total

Review 1.  Chemistry and biology of roseophilin and the prodigiosin alkaloids: a survey of the last 2500 years.

Authors:  Alois Fürstner
Journal:  Angew Chem Int Ed Engl       Date:  2003-08-11       Impact factor: 15.336

2.  Co-transport of H+/Cl- by a synthetic prodigiosin mimic.

Authors:  Philip A Gale; Mark E Light; Beth McNally; Korakot Navakhun; Kate E Sliwinski; Bradley D Smith
Journal:  Chem Commun (Camb)       Date:  2005-05-25       Impact factor: 6.222

3.  Synthesis, anion-binding properties, and in vitro anticancer activity of prodigiosin analogues.

Authors:  Jonathan L Sessler; Leah R Eller; Won-Seob Cho; Sergios Nicolaou; Apolonio Aguilar; Jeong Tae Lee; Vincent M Lynch; Darren J Magda
Journal:  Angew Chem Int Ed Engl       Date:  2005-09-19       Impact factor: 15.336

4.  Conformational control of transmembrane Cl(-) transport.

Authors:  Paul V Santacroce; Jeffery T Davis; Mark E Light; Philip A Gale; José Carlos Iglesias-Sanchez; Pilar Prados; Roberto Quesada
Journal:  J Am Chem Soc       Date:  2007-01-25       Impact factor: 15.419

Review 5.  Development of synthetic membrane transporters for anions.

Authors:  Anthony P Davis; David N Sheppard; Bradley D Smith
Journal:  Chem Soc Rev       Date:  2006-10-23       Impact factor: 54.564

6.  Rigid oligonaphthalenediimide rods as transmembrane anion-pi slides.

Authors:  Virginie Gorteau; Guillaume Bollot; Jiri Mareda; Alejandro Perez-Velasco; Stefan Matile
Journal:  J Am Chem Soc       Date:  2006-11-22       Impact factor: 15.419

7.  Enhanced Carboxylate Binding Using Urea and Amide-Based Receptors with Internal Lewis Acid Coordination: A Cooperative Polarization Effect.

Authors:  Martin Patrick Hughes; Bradley D. Smith
Journal:  J Org Chem       Date:  1997-06-27       Impact factor: 4.354

8.  Ion channel formation from a calix[4]arene amide that binds HCl.

Authors:  Vladimir Sidorov; Frank W Kotch; Galya Abdrakhmanova; Robert Mizani; James C Fettinger; Jeffery T Davis
Journal:  J Am Chem Soc       Date:  2002-03-13       Impact factor: 15.419

9.  Molecular ferries: membrane carriers that promote phospholipid flip-flop and chloride transport.

Authors:  Bradley D Smith; Timothy N Lambert
Journal:  Chem Commun (Camb)       Date:  2003-09-21       Impact factor: 6.222

10.  Heptyl prodigiosin, a bacterial metabolite, is antimalarial in vivo and non-mutagenic in vitro.

Authors:  J Enrico H Lazaro; Josiane Nitcheu; Rey Z Predicala; Gina C Mangalindan; Fabrice Nesslany; Daniel Marzin; Gisela P Concepcion; Bertrand Diquet
Journal:  J Nat Toxins       Date:  2002-12
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  6 in total

1.  Fluorescent, synthetic amphiphilic heptapeptide anion transporters: evidence for self-assembly and membrane localization in liposomes.

Authors:  Lei You; George W Gokel
Journal:  Chemistry       Date:  2008       Impact factor: 5.236

2.  Thiosquaramides: pH switchable anion transporters.

Authors:  Nathalie Busschaert; Robert B P Elmes; Dawid D Czech; Xin Wu; Isabelle L Kirby; Evan M Peck; Kevin D Hendzel; Scott K Shaw; Bun Chan; Bradley D Smith; Katrina A Jolliffe; Philip A Gale
Journal:  Chem Sci       Date:  2014-09-01       Impact factor: 9.825

3.  Using small molecules to facilitate exchange of bicarbonate and chloride anions across liposomal membranes.

Authors:  Jeffery T Davis; Philip A Gale; Oluyomi A Okunola; Pilar Prados; Jose Carlos Iglesias-Sánchez; Tomás Torroba; Roberto Quesada
Journal:  Nat Chem       Date:  2009-04-19       Impact factor: 24.427

4.  Octafluorocalix[4]pyrrole: a chloride/bicarbonate antiport agent.

Authors:  Philip A Gale; Christine C Tong; Cally J E Haynes; Olubukunola Adeosun; Dustin E Gross; Elizabeth Karnas; Elaine M Sedenberg; Roberto Quesada; Jonathan L Sessler
Journal:  J Am Chem Soc       Date:  2010-03-17       Impact factor: 15.419

5.  meso-octamethylcalix[4]pyrrole: an old yet new transmembrane ion-pair transporter.

Authors:  Christine C Tong; Roberto Quesada; Jonathan L Sessler; Philip A Gale
Journal:  Chem Commun (Camb)       Date:  2008-10-21       Impact factor: 6.222

6.  Anion transport properties of amine and amide-sidechained peptides are affected by charge and phospholipid composition.

Authors:  Lei You; Ruiqiong Li; George W Gokel
Journal:  Org Biomol Chem       Date:  2008-06-16       Impact factor: 3.876

  6 in total

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