Literature DB >> 17457103

HIV-1 genetic diversity and compartmentalization in mother/infant pairs infected with CRF01_AE.

Sodsai Tovanabutra1, Mark de Souza, Nopporn Sittisombut, Somchai Sriplienchan, Vidhaya Ketsararat, Deborah L Birx, Chirasak Khamboonrueng, Kenrad E Nelson, Francine E McCutchan, Merlin L Robb.   

Abstract

Molecular characterization of C2-V5 envelope sequences from maternal plasma, peripheral blood mononuclear cells (PBMC), cervical secretions and infant PBMC was performed in eight CRF01_AE-infected mother/infant pairs. Maternal viruses were relatively homogeneous within a compartment but distinct in different compartments in mothers with high CD4 cell counts. Infant viruses were almost distinct, but phylogenetically related, to maternal viruses, mostly from the maternal PBMC compartment, reflecting the frequent transmission of HIV-1 from maternal cells rather than free viruses.

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Year:  2007        PMID： 17457103     DOI： 10.1097/QAD.0b013e32810c8cf3

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  5 in total

1.  Infant feeding practices were not associated with breast milk HIV-1 RNA levels in a randomized clinical trial in Botswana.

Authors:  Raabya Rossenkhan; Vladimir Novitsky; Teresa K Sebunya; Jean Leidner; Jose E Hagan; Sikhulile Moyo; Laura Smeaton; Shahin Lockman; Rosemary Musonda; Thumbi Ndung'u; Simani Gaseitsiwe; Ibou Thior; Mompati Mmalane; Joseph Makhema; M Essex; Roger Shapiro
Journal:  AIDS Behav       Date:  2012-07

2.  W-curve alignments for HIV-1 genomic comparisons.

Authors:  Douglas J Cork; Steven Lembark; Sodsai Tovanabutra; Merlin L Robb; Jerome H Kim
Journal:  PLoS One       Date:  2010-06-01       Impact factor: 3.240

3.  Viral sequence analysis of HIV-positive women and their infected children: insight on the timing of infection and on the transmission network.

Authors:  Massimo Ciccozzi; Alessandra Lo Presti; Mauro Andreotti; Sandro Mancinelli; Susanna Ceffa; Clementina Maria Galluzzo; Ersilia Buonomo; Richard Luhanga; Haswell Jere; Eleonora Cella; Paola Scarcella; Marco Mirra; Maria Cristina Marazzi; Stefano Vella; Leonardo Palombi; Marina Giuliano
Journal:  AIDS Res Hum Retroviruses       Date:  2014-09-04       Impact factor: 2.205

Review 4.  Viral determinants of HIV-1 macrophage tropism.

Authors:  Christopher J A Duncan; Quentin J Sattentau
Journal:  Viruses       Date:  2011-11-15       Impact factor: 5.048

5.  Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures.

Authors:  Kyle J Nakamura; Laura Heath; Edwin R Sobrera; Thomas A Wilkinson; Katherine Semrau; Chipepo Kankasa; Nicole H Tobin; Nicholas E Webb; Benhur Lee; Donald M Thea; Louise Kuhn; James I Mullins; Grace M Aldrovandi
Journal:  Retrovirology       Date:  2017-01-26       Impact factor: 4.602
  5 in total

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