Literature DB >> 17456517

New challenges for 21st century clinical trials.

Richard Simon1.   

Abstract

Mesh：

Year:  2007        PMID： 17456517     DOI： 10.1177/1740774507076800

Source DB:  PubMed          Journal:  Clin Trials        ISSN： 1740-7745            Impact factor:   2.486


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  9 in total

1.  Testing in a Prespecified Subgroup and the Intent-to-Treat Population.

Authors:  Mark D Rothmann; Jenny J Zhang; Laura Lu; Thomas R Fleming
Journal:  Drug Inf J       Date:  2012-03-01

2.  Clinical trials for predictive medicine: new challenges and paradigms.

Authors:  Richard Simon
Journal:  Clin Trials       Date:  2010-03-25       Impact factor: 2.486

Review 3.  [Individualizing treatment for locally advanced rectal cancer].

Authors:  T Liersch; H Rothe; B M Ghadimi; H Becker
Journal:  Chirurg       Date:  2009-04       Impact factor: 0.955

4.  Multiple testing of treatment-effect-modifying biomarkers in a randomized clinical trial with a survival endpoint.

Authors:  Stefan Michiels; Richard F Potthoff; Stephen L George
Journal:  Stat Med       Date:  2011-02-23       Impact factor: 2.373

5.  Genotype-based risk and pharmacogenetic sampling in clinical trials.

Authors:  Nicholas J Schork; Eric J Topol
Journal:  J Biopharm Stat       Date:  2010-03       Impact factor: 1.051

6.  Preoperative chemoradiotherapy in locally advanced rectal cancer: correlation of a gene expression-based response signature with recurrence.

Authors:  Torsten Liersch; Marian Grade; Jochen Gaedcke; Sudhir Varma; Michael J Difilippantonio; Claus Langer; Clemens F Hess; Heinz Becker; Thomas Ried; B Michael Ghadimi
Journal:  Cancer Genet Cytogenet       Date:  2009-04-15

Review 7.  Drug-diagnostics co-development in oncology.

Authors:  Richard Simon
Journal:  Front Oncol       Date:  2013-12-23       Impact factor: 6.244

Review 8.  Statistical controversies in clinical research: prognostic gene signatures are not (yet) useful in clinical practice.

Authors:  S Michiels; N Ternès; F Rotolo
Journal:  Ann Oncol       Date:  2016-09-15       Impact factor: 32.976

9.  A new test statistic based on shrunken sample variance for identifying differentially expressed genes in small microarray experiments.

Authors:  Akihiro Hirakawa; Yasunori Sato; Chikuma Hamada; Isao Yoshimura
Journal:  Bioinform Biol Insights       Date:  2008-02-29
  9 in total

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