Literature DB >> 17454264

Regulation of type 1 diabetes by NKT cells.

Jan Novak1, Thibault Griseri, Lucie Beaudoin, Agnès Lehuen.   

Abstract

Type 1 diabetes is an autoimmune disease due to the destruction of insulin-producing pancreatic beta cells. Natural Killer T (NKT) cells are a T-cell subset that links the innate and adaptive immune systems. NKT cells play a key regulatory role in type 1 diabetes. The absence of NKT cells correlates with exacerbation of type 1 diabetes, whereas an increased frequency and/or activation of NKT cells prevents beta-cell autoimmunity. Various mechanisms are involved in the protective effect of NKT cells. The goal is now to translate knowledge gained from mouse models into human therapeutics.

Entities:  

Mesh：

Year:  2007        PMID： 17454264     DOI： 10.1080/08830180601070229

Source DB:  PubMed          Journal:  Int Rev Immunol        ISSN： 0883-0185            Impact factor:   5.311


  23 in total

Review 1.  Immune cell crosstalk in type 1 diabetes.

Authors:  Agnès Lehuen; Julien Diana; Paola Zaccone; Anne Cooke
Journal:  Nat Rev Immunol       Date:  2010-07       Impact factor: 53.106

2.  Altered peripheral invariant natural killer T cells in atopic dermatitis.

Authors:  Edit Gyimesi; Georgina Nagy; Éva Remenyik; Sándor Sipka; Margit Zeher; Tamás Bíró; Andrea Szegedi
Journal:  J Clin Immunol       Date:  2011-06-21       Impact factor: 8.317

3.  Enzymatic synthesis of Gb3 and iGb3 ceramides.

Authors:  Dietlind Adlercreutz; Joel T Weadge; Bent O Petersen; Jens Ø Duus; Norman J Dovichi; Monica M Palcic
Journal:  Carbohydr Res       Date:  2010-02-13       Impact factor: 2.104

4.  The immunosuppressive role of adenosine A2A receptors in ischemia reperfusion injury and islet transplantation.

Authors:  Preeti Chhabra; Joel Linden; Peter Lobo; Mark Douglas Okusa; Kenneth Lewis Brayman
Journal:  Curr Diabetes Rev       Date:  2012-11

Review 5.  Prevention and treatment of type 1 diabetes mellitus by the manipulation of invariant natural killer T cells.

Authors:  Jan Novak; Lucie Novakova
Journal:  Clin Exp Med       Date:  2012-07-24       Impact factor: 3.984

6.  Early activation of invariant natural killer T cells in a rheumatoid arthritis model and application to disease treatment.

Authors:  Aurore Miellot-Gafsou; Jérôme Biton; Elvire Bourgeois; André Herbelin; Marie-Christophe Boissier; Natacha Bessis
Journal:  Immunology       Date:  2010-01-27       Impact factor: 7.397

Review 7.  Presumed guilty: natural killer T cell defects and human disease.

Authors:  Stuart P Berzins; Mark J Smyth; Alan G Baxter
Journal:  Nat Rev Immunol       Date:  2011-02       Impact factor: 53.106

8.  Cells with regulatory function of the innate and adaptive immune system in primary Sjögren's syndrome.

Authors:  P Szodoray; G Papp; I F Horvath; S Barath; S Sipka; B Nakken; M Zeher
Journal:  Clin Exp Immunol       Date:  2009-09       Impact factor: 4.330

9.  Treatment with incomplete Freund's adjuvant and Listeria monocytogenes delays diabetes via an interleukin-17-secretion-independent pathway.

Authors:  Hai-Ping Wang; Zhi-Gao He
Journal:  Exp Ther Med       Date:  2015-03-03       Impact factor: 2.447

10.  CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice.

Authors:  Cheng Ye; Benjamin E Low; Michael V Wiles; Todd M Brusko; David V Serreze; John P Driver
Journal:  J Immunol       Date:  2020-08-31       Impact factor: 5.422
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.