Literature DB >> 17454057

Preparation and characterization of quercetin and rutin cyclodextrin inclusion complexes.

K Vijaya Sri1, A Kondaiah, J Vijaya Ratna, A Annapurna.   

Abstract

The objective of the present study is to prepare and characterize cyclodextrin inclusion complexes of quercetin and rutin to improve their aqueous solubility and dissolution properties. Inclusion complexes of quercetin and rutin with beta-cyclodextrin (beta-CD) and hydroxyl propyl-beta-cyclodextrin (HP-beta-CD) were prepared by kneading and coevaporation methods. Characterization of inclusion complexes was done by phase solubility analysis and was supported by X-ray powder diffractometry (XRD), differential scanning calorimetry (DSC), and Fourier-transform infra red spectroscopy (FT-IR) analysis. Inclusion complexes exhibited higher rates of dissolution than the corresponding physical mixtures and pure drug. Higher dissolution rates were observed with HP-beta-CD kneaded complexes in comparison to the products with beta-CD.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17454057     DOI： 10.1080/03639040601150195

Source DB:  PubMed          Journal:  Drug Dev Ind Pharm        ISSN： 0363-9045            Impact factor:   3.225


  10 in total

1.  Gold nanoparticle-conjugated quercetin inhibits epithelial-mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR-2-mediated pathway in breast cancer.

Authors:  S Balakrishnan; F A Bhat; P Raja Singh; S Mukherjee; P Elumalai; S Das; C R Patra; J Arunakaran
Journal:  Cell Prolif       Date:  2016-09-18       Impact factor: 6.831

2.  Quercetin/beta-cyclodextrin solid complexes prepared in aqueous solution followed by spray-drying or by physical mixture.

Authors:  Greice S Borghetti; Ivana S Lula; Ruben D Sinisterra; Valquiria L Bassani
Journal:  AAPS PharmSciTech       Date:  2009-03-12       Impact factor: 3.246

3.  Evaluation of combined famotidine with quercetin for the treatment of peptic ulcer: in vivo animal study.

Authors:  Mohammed A S Abourehab; Khaled A Khaled; Hatem A A Sarhan; Osama A A Ahmed
Journal:  Drug Des Devel Ther       Date:  2015-04-13       Impact factor: 4.162

4.  Synthesis of Quercetin Loaded Nanoparticles Based on Alginate for Pb(II) Adsorption in Aqueous Solution.

Authors:  Yun Qi; Meng Jiang; Yuan-Lu Cui; Lin Zhao; Xia Zhou
Journal:  Nanoscale Res Lett       Date:  2015-10-17       Impact factor: 4.703

5.  Quercetin solid lipid microparticles: a flavonoid for inhalation lung delivery.

Authors:  Santo Scalia; Mehra Haghi; Vanessa Losi; Valentina Trotta; Paul M Young; Daniela Traini
Journal:  Eur J Pharm Sci       Date:  2013-03-26       Impact factor: 4.384

6.  Formation of Rutin-β-Cyclodextrin Inclusion Complexes by Supercritical Antisolvent Precipitation.

Authors:  Paola Franco; Iolanda De Marco
Journal:  Polymers (Basel)       Date:  2021-01-13       Impact factor: 4.329

7.  A novel quercetin/β-cyclodextrin transdermal gel, combined or not with therapeutic ultrasound, reduces oxidative stress after skeletal muscle injury.

Authors:  Luis Fernando Sousa Filho; Marta Maria Barbosa Santos; Paula Dos Passos Menezes; Bruno Dos Santos Lima; Adriano Antunes de Souza Araújo; Evaleide Diniz de Oliveira
Journal:  RSC Adv       Date:  2021-08-17       Impact factor: 4.036

8.  Evaluation of Ulcer Protective Activity of Morus alba L. Extract-Loaded Chitosan Microspheres in Ethanol-Induced Ulcer in Rat Model.

Authors:  Sarita Garg; Rajeev K Singla; Md Mominur Rahman; Rohit Sharma; Vineet Mittal
Journal:  Evid Based Complement Alternat Med       Date:  2022-09-30       Impact factor: 2.650

9.  Rutin mediated targeting of signaling machinery in cancer cells.

Authors:  Aliye Aras Perk; Iryna Shatynska-Mytsyk; Yusuf Can Gerçek; Kadir Boztaş; Mevzule Yazgan; Sundas Fayyaz; Ammad Ahmad Farooqi
Journal:  Cancer Cell Int       Date:  2014-11-30       Impact factor: 5.722

10.  Stealth lipid polymer hybrid nanoparticles loaded with rutin for effective brain delivery - comparative study with the gold standard (Tween 80): optimization, characterization and biodistribution.

Authors:  Rania A H Ishak; Nada M Mostafa; Amany O Kamel
Journal:  Drug Deliv       Date:  2017-11       Impact factor: 6.419
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.