Literature DB >> 17453338

Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis.

Tanja Langsenlehner, Wilfried Renner, Babak Yazdani-Biuki, Uwe Langsenlehner.   

Abstract

Encouraged by recent studies on the MTHFR 677C>T polymorphism and breast cancer risk that suggested an association of the 677 TT genotype with increased breast cancer susceptibility in premenopausal women, we performed an analysis of the relationship between breast cancer risk and the MTHFR 677C>T polymorphism in 210 premenopausal breast cancer patients and sex- and agematched healthy control subjects. Our data show a trend for a higher MTHFR 677T allele frequency in breast cancer cases (61.9%) than in controls (51.5%, P = 0.082) supporting the results of previous studies.

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Year:  2007        PMID: 17453338     DOI: 10.1007/s10549-007-9564-1

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN: 0167-6806            Impact factor:   4.872


  13 in total

1.  [Genotype of the GNB3 C825T polymorphism, A risk factor for the development and course of prostate cancer?].

Authors:  A Eisenhardt; A Scherag; M Kempin; K H Jöckel; H Rübben
Journal:  Urologe A       Date:  2011-09       Impact factor: 0.639

2.  The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and tumor risk: evidence from 134 case-control studies.

Authors:  Min Tang; Shang-Qian Wang; Bian-Jiang Liu; Qiang Cao; Bing-Jie Li; Peng-Chao Li; Yong-Fei Li; Chao Qin; Wei Zhang
Journal:  Mol Biol Rep       Date:  2014-04-18       Impact factor: 2.316

3.  A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in breast cancer.

Authors:  Shanliang Zhong; Zhiyuan Chen; Xinnian Yu; Wenjing Li; Jinhai Tang; Jianhua Zhao
Journal:  Mol Biol Rep       Date:  2014-06-29       Impact factor: 2.316

Review 4.  Association of MTHFR Ala222Val (rs1801133) polymorphism and breast cancer susceptibility: An update meta-analysis based on 51 research studies.

Authors:  Liwa Yu; Jianqiu Chen
Journal:  Diagn Pathol       Date:  2012-12-07       Impact factor: 2.644

Review 5.  Methylenetetrahydrofolate reductase gene C677T polymorphism and breast cancer risk: Evidence for genetic susceptibility.

Authors:  Pradeep Kumar; Upendra Yadav; Vandana Rai
Journal:  Meta Gene       Date:  2015-10-01

6.  Dietary intake of vitamin B(6) and risk of breast cancer in Taiwanese women.

Authors:  Yu-Ching Chou; Chi-Hong Chu; Mei-Hsuan Wu; Giu-Cheng Hsu; Tsan Yang; Wan-Yun Chou; Hsin-Ping Huang; Meei-Shyuan Lee; Cheng-Ping Yu; Jyh-Cherng Yu; Chien-An Sun
Journal:  J Epidemiol       Date:  2011-06-25       Impact factor: 3.211

7.  Association of 677 C>T (rs1801133) and 1298 A>C (rs1801131) polymorphisms in the MTHFR gene and breast cancer susceptibility: a meta-analysis based on 57 individual studies.

Authors:  Kai Li; Wusheng Li; Xi Dong
Journal:  PLoS One       Date:  2014-06-19       Impact factor: 3.240

8.  Association between the methylenetetrahydrofolate reductase C677T polymorphism and hepatocellular carcinoma risk: a meta-analysis.

Authors:  Fei Jin; Li-Shuai Qu; Xi-Zhong Shen
Journal:  Diagn Pathol       Date:  2009-11-24       Impact factor: 2.644

9.  MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study.

Authors:  Sonia S Maruti; Cornelia M Ulrich; Eldon R Jupe; Emily White
Journal:  Breast Cancer Res       Date:  2009-12-23       Impact factor: 6.466

10.  Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women.

Authors:  Enbo Ma; Motoki Iwasaki; Ishihara Junko; Gerson Shigeaki Hamada; Ines Nobuko Nishimoto; Solange Maria Torchia Carvalho; Juvenal Motola; Fábio Martins Laginha; Shoichiro Tsugane
Journal:  BMC Cancer       Date:  2009-04-24       Impact factor: 4.430

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