Literature DB >> 1745318

The effect of tranexamic acid on bleeding time and haemostasis.

S A Menzies1, J A Hartley, E R Hitchcock, E Rorke, J S Gill.   

Abstract

The effect of tranexamic acid (TXA) on platelet function was examined in 37 patients with ruptured intracranial aneurysms. TXA was administered in a double-blind, placebo controlled manner to 37 patients with ruptured intracranial aneurysms. TXA was given to 17 patients in a dose of 9 g/24 hours, to another 6 patients in a dose of 6 g/24 hours; 14 patients were given a placebo. The effect of TXA on certain haemostatic function tests was evaluated between the treatment groups. We conclude that patients receiving TXA do not appear to be at risk of recurrent haemorrhage due to abnormal haemostasis.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 1745318     DOI: 10.1055/s-2008-1052074

Source DB:  PubMed          Journal:  Neurochirurgia (Stuttg)        ISSN: 0028-3819


  2 in total

1.  Prophylactic hemostatic drugs do not reduce hemorrhage: Thromboelastographic study during upper abdominal surgery.

Authors:  H Hamada; M Senami; K Fujii; K Sera; A Kobayashi; M Kuroda
Journal:  J Anesth       Date:  1995-03       Impact factor: 2.078

Review 2.  Tranexamic acid: a review of its use in the management of menorrhagia.

Authors:  Keri Wellington; Antona J Wagstaff
Journal:  Drugs       Date:  2003       Impact factor: 9.546

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.