Literature DB >> 17452480

Role of the ABC transporter PRP1 (ABCC7) in pentamidine resistance in Leishmania amastigotes.

Adriano C Coelho1, Nadine Messier, Marc Ouellette, Paulo C Cotrim.   

Abstract

Pentamidine is a second-line agent in the treatment of leishmaniasis whose mode of action and resistance mechanism are not well understood. In this work, we show that the intracellular ABC protein PRP1 (pentamidine resistance protein 1) (ABCC7) can confer resistance to pentamidine in Leishmania sp. parasites in the intracellular stage.

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Year:  2007        PMID： 17452480      PMCID： PMC1932501          DOI： 10.1128/AAC.00404-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  27 in total

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Authors:  E Ghedin; A Debrabant; J C Engel; D M Dwyer
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Review 2.  The human ATP-binding cassette (ABC) transporter superfamily.

Authors:  M Dean; A Rzhetsky; R Allikmets
Journal:  Genome Res       Date:  2001-07       Impact factor: 9.043

3.  The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase.

Authors:  D Légaré; D Richard; R Mukhopadhyay; Y D Stierhof; B P Rosen; A Haimeur; B Papadopoulou; M Ouellette
Journal:  J Biol Chem       Date:  2001-04-16       Impact factor: 5.157

4.  Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani.

Authors:  Angana Mukherjee; Prasad K Padmanabhan; Sushma Singh; Gaétan Roy; Isabelle Girard; Mitali Chatterjee; Marc Ouellette; Rentala Madhubala
Journal:  J Antimicrob Chemother       Date:  2007-01-09       Impact factor: 5.790

5.  Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion.

Authors:  Mireille Basselin; Hubert Denise; Graham H Coombs; Michael P Barrett
Journal:  Antimicrob Agents Chemother       Date:  2002-12       Impact factor: 5.191

6.  DNA transformation of Leishmania infantum axenic amastigotes and their use in drug screening.

Authors:  D Sereno; G Roy; J L Lemesre; B Papadopoulou; M Ouellette
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

7.  Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana.

Authors:  K A Mullin; B J Foth; S C Ilgoutz; J M Callaghan; J L Zawadzki; G I McFadden; M J McConville
Journal:  Mol Biol Cell       Date:  2001-08       Impact factor: 4.138

8.  Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models.

Authors:  G Roy; C Dumas; D Sereno; Y Wu; A K Singh; M J Tremblay; M Ouellette; M Olivier; B Papadopoulou
Journal:  Mol Biochem Parasitol       Date:  2000-10       Impact factor: 1.759

Review 9.  Multidrug resistance phenotype mediated by the P-glycoprotein-like transporter in Leishmania: a search for reversal agents.

Authors:  J M Pérez-Victoria; A Di Pietro; D Barron; A G Ravelo; S Castanys; F Gamarro
Journal:  Curr Drug Targets       Date:  2002-08       Impact factor: 3.465

10.  Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major.

Authors:  Adriano C Coelho; Stephen M Beverley; Paulo C Cotrim
Journal:  Mol Biochem Parasitol       Date:  2003-08-31       Impact factor: 1.759
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Authors: 
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Authors:  Mohammad Javad Boozhmehrani; Gilda Eslami; Ali Khamesipour; Abbas Ali Jafari; Mahmood Vakili; Saeedeh Sadat Hosseini; Vahideh Askari
Journal:  AMB Express       Date:  2022-06-16       Impact factor: 4.126

3.  A new ABC half-transporter in Leishmania major is involved in resistance to antimony.

Authors:  J I Manzano; R García-Hernández; S Castanys; F Gamarro
Journal:  Antimicrob Agents Chemother       Date:  2013-05-28       Impact factor: 5.191

4.  ABCI3 Is a New Mitochondrial ABC Transporter from Leishmania major Involved in Susceptibility to Antimonials and Infectivity.

Authors:  Talia Arcari; José Ignacio Manzano; Francisco Gamarro
Journal:  Antimicrob Agents Chemother       Date:  2017-11-22       Impact factor: 5.191

5.  Geographical Distribution of MDR1 Expression in Leishmania Isolates, from Greece and Cyprus, Measured by the Rhodamine-123 Efflux Potential of the Isolates, Using Flow Cytometry.

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Journal:  Am J Trop Med Hyg       Date:  2016-03-21       Impact factor: 2.345

6.  Antimony resistance during Visceral Leishmaniasis: A possible consequence of serial mutations in ABC transporters of Leishmania species.

Authors:  Sukrat Sinha; Shanthy Sundaram; Vijay Kumar; Ashutosh Tripathi
Journal:  Bioinformation       Date:  2011-04-22

Review 7.  Comparative analysis of the omics technologies used to study antimonial, amphotericin B, and pentamidine resistance in leishmania.

Authors:  Gagandeep Kaur; Bhawana Rajput
Journal:  J Parasitol Res       Date:  2014-05-12

Review 8.  New Approaches to Overcome Transport Related Drug Resistance in Trypanosomatid Parasites.

Authors:  Jose A Garcia-Salcedo; Juan D Unciti-Broceta; Javier Valverde-Pozo; Miguel Soriano
Journal:  Front Pharmacol       Date:  2016-09-28       Impact factor: 5.810

9.  Drug resistance in natural isolates of Leishmania donovani s.l. promastigotes is dependent of Pgp170 expression.

Authors:  Ippokratis Messaritakis; Vasiliki Christodoulou; Apostolos Mazeris; Eleni Koutala; Antonia Vlahou; Sevasti Papadogiorgaki; Maria Antoniou
Journal:  PLoS One       Date:  2013-06-11       Impact factor: 3.240

10.  Identification and bioinformatic characterization of a multidrug resistance associated protein (ABCC) gene in Plasmodium berghei.

Authors:  María González-Pons; Ada C Szeto; Ricardo González-Méndez; Adelfa E Serrano
Journal:  Malar J       Date:  2009-01-02       Impact factor: 2.979
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