PURPOSE: Comparison of pregnancy rates in cases of Secretory Azoospermias (SA), Obstructive Azoospermias (OA) and severe Oligoasthenoteratozoospermias (OATZ). Evaluation of sperm motility as a quality criterion. METHODS: In SA cases (n = 35), 9 samples were cryopreserved. In OA cases (epididymal aspiration: n = 91; testicular biopsy: n = 206), all samples were cryopreserved. 596 OATZ ejaculates were included. RESULTS: In SA cases, 2 pregnancies were achieved from 9 ICSI cycles. In OA, motile sperm rates were higher in testicular biopsies. After thawing sperm motility was not different between testicular and epididymal origin. 2 pregnancies were achieved with immotile testicular sperm after thawing, but none with immotile epididymal sperm. In OATZ cases, one pregnancy was obtained from the 9 cryopreserved ejaculates and 35.3% with fresh motile sperm. CONCLUSIONS: In SA cases, the use of donor sperm is recommended due to the lower pregnancy rate achieved. Motility, before and after cryopreservation, as a criterion of sperm viability is discussed and its use should be reconsidered in some cases.
PURPOSE: Comparison of pregnancy rates in cases of Secretory Azoospermias (SA), Obstructive Azoospermias (OA) and severe Oligoasthenoteratozoospermias (OATZ). Evaluation of sperm motility as a quality criterion. METHODS: In SA cases (n = 35), 9 samples were cryopreserved. In OA cases (epididymal aspiration: n = 91; testicular biopsy: n = 206), all samples were cryopreserved. 596 OATZ ejaculates were included. RESULTS: In SA cases, 2 pregnancies were achieved from 9 ICSI cycles. In OA, motile sperm rates were higher in testicular biopsies. After thawing sperm motility was not different between testicular and epididymal origin. 2 pregnancies were achieved with immotile testicular sperm after thawing, but none with immotile epididymal sperm. In OATZ cases, one pregnancy was obtained from the 9 cryopreserved ejaculates and 35.3% with fresh motile sperm. CONCLUSIONS: In SA cases, the use of donor sperm is recommended due to the lower pregnancy rate achieved. Motility, before and after cryopreservation, as a criterion of sperm viability is discussed and its use should be reconsidered in some cases.
Authors: Z P Nagy; J Liu; H Joris; G Verheyen; H Tournaye; M Camus; M C Derde; P Devroey; A C Van Steirteghem Journal: Hum Reprod Date: 1995-05 Impact factor: 6.918
Authors: H Tournaye; J Liu; P Z Nagy; M Camus; A Goossens; S Silber; A C Van Steirteghem; P Devroey Journal: Hum Reprod Date: 1996-01 Impact factor: 6.918
Authors: M Nijs; P Vanderzwalmen; B Vandamme; G Segal-Bertin; B Lejeune; L Segal; E van Roosendaal; R Schoysman Journal: Hum Reprod Date: 1996-10 Impact factor: 6.918
Authors: I Madgar; A Hourvitz; J Levron; D S Seidman; A Shulman; G G Raviv; D Levran; D Bider; S Mashiach; J Dor Journal: Fertil Steril Date: 1998-06 Impact factor: 7.329