OBJECTS: To show the clinical results of a corpus callosotomy (CC) treatment using conformal stereotactic radiosurgery (SRS) on a patient with medically intractable multifocal epilepsy. MATERIALS AND METHODS: A 17-year-old male patient underwent corpus callosotomy conformal SRS using a dedicated linear accelerator (linac) with dynamic arcs technique. The prescribed dose was 36.0 Gy at the periphery of the rostrum, genu, and a half of the body of the corpus callosum (CCA). At 8 months after conformal SRS, the patient developed a significant brain edema and moderate transitory motor deficit, which were controlled with steroids. After 32 months follow-up, there is an improvement of 84% on drop attacks and generalized tonic-clonic seizures. CONCLUSIONS: Conformal SRS for corpus callosotomy with a single isocenter reproduce the results reported on literature using Gamma Knife-based SRS. The results show that this technique is safe and demonstrate its efficacy to control seizures.
OBJECTS: To show the clinical results of a corpus callosotomy (CC) treatment using conformal stereotactic radiosurgery (SRS) on a patient with medically intractable multifocal epilepsy. MATERIALS AND METHODS: A 17-year-old male patient underwent corpus callosotomy conformal SRS using a dedicated linear accelerator (linac) with dynamic arcs technique. The prescribed dose was 36.0 Gy at the periphery of the rostrum, genu, and a half of the body of the corpus callosum (CCA). At 8 months after conformal SRS, the patient developed a significant brain edema and moderate transitory motor deficit, which were controlled with steroids. After 32 months follow-up, there is an improvement of 84% on drop attacks and generalized tonic-clonic seizures. CONCLUSIONS: Conformal SRS for corpus callosotomy with a single isocenter reproduce the results reported on literature using Gamma Knife-based SRS. The results show that this technique is safe and demonstrate its efficacy to control seizures.
Authors: A Quattrini; M Del Pesce; L Provinciali; R Cesarano; A Ortenzi; A Paggi; F Rychlicki; P Fioravanti; I Papo Journal: J Neurosurg Sci Date: 1997-03 Impact factor: 2.279
Authors: Hans Georg Eder; Michael Feichtinger; Tom Pieper; Senta Kurschel; Oskar Schroettner Journal: Childs Nerv Syst Date: 2006-06-13 Impact factor: 1.475
Authors: Michael Feichtinger; Oskar Schröttner; Hans Eder; Hans Holthausen; Tom Pieper; Frank Unger; Alexander Holl; Lucia Gruber; Eva Körner; Eugen Trinka; Franz Fazekas; Erwin Ott Journal: Epilepsia Date: 2006-07 Impact factor: 5.864