| Literature DB >> 1744931 |
A E Waterman1, A Livingston, A Amin.
Abstract
The thermal and mechanical analgesic profile of buprenorphine at a dose rate of 1.5 micrograms/kg i.v. was investigated in five sheep. This dose produced significant analgesia for 40 min against the thermal stimulus, but no mechanical antinociception. A higher dose rate of 12 micrograms/kg also failed to produce antinociception to a mechanical stimulus. In addition, the effect of the drug (6 micrograms/kg) on respiratory gas tensions was determined and no significant changes were observed.Entities:
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Year: 1991 PMID： 1744931 DOI： 10.1111/j.1365-2885.1991.tb00831.x
Source DB: PubMed Journal: J Vet Pharmacol Ther ISSN： 0140-7783 Impact factor: 1.786