| Literature DB >> 17449075 |
Marc Sautour1, Tomofumi Miyamoto, Marie-Aleth Lacaille-Dubois.
Abstract
Six new steroidal saponins (1-6) were isolated from the roots of A. acutifolius L., together with a known spirostanol glycoside (7). Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D NMR, FABMS and HRESIMS). Compounds 4-7 demonstrated antifungal activity against the human pathogenic yeasts C. albicans, C. glabrata and C. tropicalis with MICs values between 12.5 and 100 microg/ml.Entities:
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Year: 2007 PMID： 17449075 DOI： 10.1016/j.phytochem.2007.02.033
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072