Literature DB >> 17448656

Bridged androstenediol analogs as ER-beta selective SERMs.

Timothy A Blizzard1, Candido Gude, Wanda Chan, Elizabeth T Birzin, Marina Mojena, Consuelo Tudela, Fang Chen, Kristin Knecht, Qin Su, Bryan Kraker, Mark A Holmes, Susan P Rohrer, Milton L Hammond.   

Abstract

A series of bridged androstenediol derivatives was prepared. The bridged compounds exhibited reduced ER-beta selectivity relative to uncyclized analogs.

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Year:  2006        PMID: 17448656     DOI: 10.1016/j.bmcl.2006.12.053

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

Review 1.  Structural and Functional Diversity of Estrogen Receptor Ligands.

Authors:  Amjad Farooq
Journal:  Curr Top Med Chem       Date:  2015       Impact factor: 3.295

  1 in total

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