| Literature DB >> 17446696 |
Noriyuki Okujo, Hironobu Iinuma, Annie George, Khor Siew Eim, Tan Lee Li, Ng Szu Ting, Tan Chin Jye, Kunimoto Hotta, Masahiro Hatsu, Yasuo Fukagawa, Seiji Shibahara, Keiichi Numata, Shinichi Kondo.
Abstract
Seven new related compounds named bispolides A1, A2, A3, B1, B2a, B2b and B3, have been found in a culture of Microbispora sp. A34030, isolated from a Malaysian soil sample. The planar structures were elucidated to be new 20-membered ring macrodiolide antibiotics on the basis of MS and NMR spectroscopic analyses. These antibiotics showed a good anti-MRSA activity in vitro.Entities:
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Year: 2007 PMID： 17446696 DOI： 10.1038/ja.2007.26
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649