| Literature DB >> 17446394 |
Abstract
When first reported 4 years ago, gametogenesis from embryonic stem (ES) cells promised an accessible in vitro model to facilitate molecular analysis of the germ lineage. Formation of primordial germ cells is robust, but terminal gametogenesis remains inefficient and doubts about gamete function persist. Although useful for research, clinical use of ES cell-derived gametes appears a distant prospect.Mesh:
Year: 2007 PMID: 17446394 DOI: 10.1126/science.1138772
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728