Literature DB >> 17446375

Comment on "Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens".

Fuli Yu1, R Sean Hill, Stephen F Schaffner, Pardis C Sabeti, Eric T Wang, Andre A Mignault, Russell J Ferland, Robert K Moyzis, Christopher A Walsh, David Reich.   

Abstract

Mekel-Bobrov et al. (Reports, 9 September 2005, p. 1720) suggested that ASPM, a gene associated with microcephaly, underwent natural selection within the last 500 to 14,100 years. Their analyses based on comparison with computer simulations indicated that ASPM had an unusual pattern of variation. However, when we compare ASPM empirically to a large number of other loci, its variation is not unusual and does not support selection.

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Year:  2007        PMID： 17446375     DOI： 10.1126/science.1137568

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

Review 1.  Recent and ongoing selection in the human genome.

Authors:  Rasmus Nielsen; Ines Hellmann; Melissa Hubisz; Carlos Bustamante; Andrew G Clark
Journal:  Nat Rev Genet       Date:  2007-11       Impact factor: 53.242

Review 2.  Explaining human uniqueness: genome interactions with environment, behaviour and culture.

Authors:  Ajit Varki; Daniel H Geschwind; Evan E Eichler
Journal:  Nat Rev Genet       Date:  2008-10       Impact factor: 53.242

Review 3.  Human evolutionary genomics: ethical and interpretive issues.

Authors:  Joseph J Vitti; Mildred K Cho; Sarah A Tishkoff; Pardis C Sabeti
Journal:  Trends Genet       Date:  2012-01-20       Impact factor: 11.639

Review 4.  Genetic correlates of the evolving primate brain.

Authors:  Eric J Vallender
Journal:  Prog Brain Res       Date:  2012       Impact factor: 2.453

Review 5.  Ethical, legal, social, and policy implications of behavioral genetics.

Authors:  Colleen M Berryessa; Mildred K Cho
Journal:  Annu Rev Genomics Hum Genet       Date:  2013-02-28       Impact factor: 8.929

6.  Sex-dependent association of common variants of microcephaly genes with brain structure.

Authors:  Lars M Rimol; Ingrid Agartz; Srdjan Djurovic; Andrew A Brown; J Cooper Roddey; Anna K Kähler; Morten Mattingsdal; Lavinia Athanasiu; Alexander H Joyner; Nicholas J Schork; Eric Halgren; Kjetil Sundet; Ingrid Melle; Anders M Dale; Ole A Andreassen
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-22       Impact factor: 11.205

Review 7.  Exploring the origins of the human brain through molecular evolution.

Authors:  Eric J Vallender
Journal:  Brain Behav Evol       Date:  2008-10-07       Impact factor: 1.808

8.  Population genetic analysis of the N-acylsphingosine amidohydrolase gene associated with mental activity in humans.

Authors:  Hie Lim Kim; Yoko Satta
Journal:  Genetics       Date:  2008-02-01       Impact factor: 4.562

9.  Detecting natural selection by empirical comparison to random regions of the genome.

Authors:  Fuli Yu; Alon Keinan; Hua Chen; Russell J Ferland; Robert S Hill; Andre A Mignault; Christopher A Walsh; David Reich
Journal:  Hum Mol Genet       Date:  2009-09-25       Impact factor: 6.150

Review 10.  Primary microcephaly: do all roads lead to Rome?

Authors:  Gemma K Thornton; C Geoffrey Woods
Journal:  Trends Genet       Date:  2009-10-21       Impact factor: 11.639
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