| Literature DB >> 17445960 |
Genevieve Degols1, Patrick Eldin, Nadir Mechti.
Abstract
The interferon (IFN) system is a major effector of the innate immunity that allows time for the subsequent establishment of an adaptive immune response against wide-range pathogens. The effectiveness of IFN to control initial infection requires the cooperation between several pathways induced in the target cells. Recent studies that highlight the implication of the 3'-5' exonuclease ISG20 (IFN Stimulated Gene product of 20 kDa) in the host's defenses against pathogens are summarised in this review.Entities:
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Year: 2007 PMID: 17445960 DOI: 10.1016/j.biochi.2007.03.006
Source DB: PubMed Journal: Biochimie ISSN: 0300-9084 Impact factor: 4.079