| Literature DB >> 17445950 |
Mauro Vieira de Almeida1, Mireille Le Hyaric, Giovanni Wilson Amarante, Maria Cristina Silva Lourenço, Marcelo Luiz Lima Brandão.
Abstract
Mono- and diacylated derivatives of galactopyranosyl amines were obtained from d-galactose, via aminated intermediates prepared by reaction of 6-deoxy-6-iodo-1,2:3,4-di-O-isopropylidene-alpha-d-galactopyranose with 1,3-propanediamine, 1,2-ethanediamine or ethanolamine. Monoacylated derivatives displayed antitubercular activity.Entities:
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Year: 2007 PMID： 17445950 DOI： 10.1016/j.ejmech.2007.01.009
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514