Literature DB >> 17445575

Stem cell therapy-present status.

H M Aejaz1, A K Aleem, N Parveen, M N Khaja, M Lakshmi Narusu, C M Habibullah.   

Abstract

Stem cell research is a new field that is advancing at an incredible pace with new discoveries being reported from all over the world. Scientists have for years looked for ways to use stem cells to replace cells and tissues that are damaged or diseased. Stem cells are the foundation cells for every organ, tissue, and cell in the body. Stem cells are undifferentiated, "blank" cells that do not yet have a specific function. Under proper conditions, stem cells begin to develop into specialized tissues and organs. They are self-sustaining and can replicate themselves for long periods of time. Embryonic stem cells are pluripotent cells, isolated from the inner cell mass of the blastocyst-stage mammalian embryo. They have the ability to differentiate into several somatic or somatic-like functional cells such as neurons, hepatocytes, cardiomyocytes, and others. Adult stem cells are specialized cells found within many tissues of the body where they function in tissue homeostasis and repair. They are precursor cells capable of differentiation into several different cells. The knowledge of stem cells from various sources offered a new hope for the treatment of various diseases.

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Year:  2007        PMID: 17445575     DOI: 10.1016/j.transproceed.2007.01.069

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  4 in total

1.  Mechanical loading of stem cells for improvement of transplantation outcome in a model of acute myocardial infarction: the role of loading history.

Authors:  Theresa R Cassino; Lauren Drowley; Masaho Okada; Sarah A Beckman; Bradley Keller; Kimimasa Tobita; Philip R Leduc; Johnny Huard
Journal:  Tissue Eng Part A       Date:  2012-03-07       Impact factor: 3.845

2.  Induction of differentiation by down-regulation of Nanog and Rex-1 in cord blood derived unrestricted somatic stem cells.

Authors:  Lida Langroudi; Mehdi Forouzandeh; Masoud Soleimani; Amir Atashi; Azadeh Fahim Golestaneh
Journal:  Mol Biol Rep       Date:  2013-05-10       Impact factor: 2.316

3.  Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells.

Authors:  Susanna Tomasoni; Lorena Longaretti; Cinzia Rota; Marina Morigi; Sara Conti; Elisa Gotti; Chiara Capelli; Martino Introna; Giuseppe Remuzzi; Ariela Benigni
Journal:  Stem Cells Dev       Date:  2012-12-21       Impact factor: 3.272

4.  Stem cell therapy for the treatment of parasitic infections: is it far away?

Authors:  Yan Zhang; Jing-Yi Mi; Yong-Jun Rui; Yong-Liang Xu; Wei Wang
Journal:  Parasitol Res       Date:  2013-11-26       Impact factor: 2.289

  4 in total

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