PURPOSE: To assess the clinical effect of pars plana vitrectomy (PPV) with intravitreous antibiotic drugs or silicone oil endotamponade in post-traumatic endophthalmitis on eyes without detachment of the retina. METHODS: Thirty cases of eyes with penetrating injury associated with endophthalmitis without retina detachment had been treated with PPV plus intravitreous antibiotic drugs or silicone oil tamponade. All the patients in the study received intravenous, subconjunctival and topical medications antibiotics. RESULTS: All the patients were followed up for 3 to 12 months. Postoperative intraocular infection of 30 eyes (30 patients) were controlled. The best-corrected visual acuity was significantly improved in both groups postoperatively (P < 0.05). The rate of postoperative retinal detachment in the PPV combined with intravitreal antibiotics group was 21.1% (4/19) vs. 9% (1/11)in the PPV combined with silicone oil There was no significant difference in postoperative endotamponade group. There was no significant difference in postoperative complications between two groups. CONCLUSIONS: PPV combined with silicone oil tamponade may have beneficial effect on the surgical treatment of traumatic bacterial endophthalmitis associated without retinal detachment, but the surgery may be used in some cases which have bad retinal condition or uncontrollable inflammation.
PURPOSE: To assess the clinical effect of pars plana vitrectomy (PPV) with intravitreous antibiotic drugs or silicone oil endotamponade in post-traumatic endophthalmitis on eyes without detachment of the retina. METHODS: Thirty cases of eyes with penetrating injury associated with endophthalmitis without retina detachment had been treated with PPV plus intravitreous antibiotic drugs or silicone oil tamponade. All the patients in the study received intravenous, subconjunctival and topical medications antibiotics. RESULTS: All the patients were followed up for 3 to 12 months. Postoperative intraocular infection of 30 eyes (30 patients) were controlled. The best-corrected visual acuity was significantly improved in both groups postoperatively (P < 0.05). The rate of postoperative retinal detachment in the PPV combined with intravitreal antibiotics group was 21.1% (4/19) vs. 9% (1/11)in the PPV combined with silicone oil There was no significant difference in postoperative endotamponade group. There was no significant difference in postoperative complications between two groups. CONCLUSIONS:PPV combined with silicone oil tamponade may have beneficial effect on the surgical treatment of traumatic bacterial endophthalmitis associated without retinal detachment, but the surgery may be used in some cases which have bad retinal condition or uncontrollable inflammation.