| Literature DB >> 17442684 |
Dominique Levêque1, François Jehl.
Abstract
This review focuses on the published data regarding the molecular determinants (enzymes, transporters, orphan nuclear receptors) of Catharanthus (vinca) alkaloids pharmacokinetics in humans. The clinical impact of these determinants (drug disposition, drug-drug interactions) is also discussed.Entities:
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Year: 2007 PMID: 17442684 DOI: 10.1177/0091270007299430
Source DB: PubMed Journal: J Clin Pharmacol ISSN: 0091-2700 Impact factor: 3.126