| Literature DB >> 17442567 |
Katarina Flyrén1, Lars O Bergquist, Victor M Castro, Christopher Fotsch, Lars Johansson, David J St Jean, Lori Sutin, Meredith Williams.
Abstract
A series of piperidine amide inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) were identified via modifications of the HTS hit compound 1. The synthesis, in vitro biological evaluation, and structure-activity relationship of these compounds are presented.Entities:
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Year: 2007 PMID： 17442567 DOI： 10.1016/j.bmcl.2007.03.083
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823