Literature DB >> 17439893

Immunosuppressive therapy is more effective than interferon in neuromyelitis optica.

C Papeix1, J-S Vidal, J de Seze, C Pierrot-Deseilligny, A Tourbah, B Stankoff, C Lebrun, T Moreau, P Vermersch, B Fontaine, O Lyon-Caen, O Gout.   

Abstract

To determine long-term treatment (LTT) of neuromyelitis optica (NMO), we retrospectively reviewed therapies of 26 patients with NMO followed in five French neurological departments. To assess LTT efficacy, the probability of relapse free after LTT was analysed. Patients were divided into two groups according to the first treatment receiving interferon beta (IFN Group, seven patients) or immunosuppressants (IS Group, 19 patients). The probability of relapse was significantly lower in the IS Group (P =0.0007). From our results, interferon beta is not recommended, and one of the best current therapeutic options for NMO appears to be immunosuppressants.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17439893     DOI: 10.1177/1352458506070732

Source DB:  PubMed          Journal:  Mult Scler        ISSN: 1352-4585            Impact factor:   6.312


  53 in total

Review 1.  A differential diagnosis of central nervous system demyelination: beyond multiple sclerosis.

Authors:  Christopher Eckstein; Shiv Saidha; Michael Levy
Journal:  J Neurol       Date:  2011-09-20       Impact factor: 4.849

2.  Treatment of neuromyelitis optica: current debate.

Authors:  Tomoko Okamoto; Masafumi Ogawa; Youwei Lin; Miho Murata; Sachiko Miyake; Takashi Yamamura
Journal:  Ther Adv Neurol Disord       Date:  2008-07       Impact factor: 6.570

Review 3.  Isolated, relapsing and progressive demyelinating diseases of the central nervous system.

Authors:  Axel Petzold
Journal:  J Neurol       Date:  2008-12       Impact factor: 4.849

4.  Neuromyelitis and more: the unfolding spectrum of aquaporin 4-related neurological diseases.

Authors:  Orhan Aktas; Hans-Peter Hartung
Journal:  J Neurol       Date:  2009-11       Impact factor: 4.849

5.  "A rose by any other name": does defining extreme phenotypes add to the management of multiple sclerosis?

Authors:  Evan A Jolliffe; Brian G Weinshenker
Journal:  Ann Transl Med       Date:  2018-10

6.  [Therapeutic options for autoimmune encephalomyelitis].

Authors:  N Borisow; H Prüss; F Paul
Journal:  Nervenarzt       Date:  2013-04       Impact factor: 1.214

Review 7.  Immunology of neuromyelitis optica: a T cell-B cell collaboration.

Authors:  Meike Mitsdoerffer; Vijay Kuchroo; Thomas Korn
Journal:  Ann N Y Acad Sci       Date:  2013-04       Impact factor: 5.691

8.  Differential diagnosis of suspected multiple sclerosis: a consensus approach.

Authors:  D H Miller; B G Weinshenker; M Filippi; B L Banwell; J A Cohen; M S Freedman; S L Galetta; M Hutchinson; R T Johnson; L Kappos; J Kira; F D Lublin; H F McFarland; X Montalban; H Panitch; J R Richert; S C Reingold; C H Polman
Journal:  Mult Scler       Date:  2008-09-19       Impact factor: 6.312

9.  Aquaporin-4 autoantibodies in neuromyelitis optica spectrum disorders: comparison between tissue-based and cell-based indirect immunofluorescence assays.

Authors:  Koon H Chan; Jason S C Kwan; Philip W L Ho; Jessica W M Ho; Andrew C Y Chu; David B Ramsden
Journal:  J Neuroinflammation       Date:  2010-09-07       Impact factor: 8.322

10.  Visual field defects of optic neuritis in neuromyelitis optica compared with multiple sclerosis.

Authors:  Hideto Nakajima; Takafumi Hosokawa; Masakazu Sugino; Fumiharu Kimura; Jun Sugasawa; Toshiaki Hanafusa; Toshiyuki Takahashi
Journal:  BMC Neurol       Date:  2010-06-18       Impact factor: 2.474

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.