Literature DB >> 17438245

Slide tracheoplasty applied to acquired subglottic and upper tracheal stenosis: an experimental study in a canine model.

Wael M Abdelkafy1, Mohamed N El Atriby, Nagy M Iskandar, Douglas E Mattox, Kamal A Mansour.   

Abstract

OBJECTIVE: To assess the applicability and complications of slide tracheoplasty in the management of subglottic and upper tracheal stenosis in experimental animals.
DESIGN: Subglottic stenosis was induced in 10 dogs by cauterizing the subglottic area and the upper 3 to 4 cm of the trachea. After 21 days, the severity of stenosis ranged from 30% to 60%. The subglottic area was reconstruction with slide tracheoplasty, and the results were evaluated at 4, 12, and 24 weeks postoperatively.
SUBJECTS: Ten mongrel dogs (Canis familiaris) were included in the study, each weighing between 12 and 17 kg. INTERVENTION: Slide tracheoplasty. MAIN OUTCOME MEASURE: Patency of the reconstructed segment.
RESULTS: Follow-up examination revealed no airway obstruction in any animal. Examination of the reconstructed segment revealed good healing without granulation tissue and a patent endotracheal lumen in all cases. Histopathological examination of sections taken at the suture line confirmed complete healing without granulation tissue.
CONCLUSIONS: Slide tracheoplasty can be applied successfully to the subglottic area. It offers many advantages in tracheal reconstruction and can be used for the management of acquired subglottic stenosis. The vascularized tracheal cartilage heals without granulation tissue often seen after cartilage interposition grafts. Furthermore, this technique reduces the need for tracheal and laryngeal mobilization for the treatment of longer areas of stenosis.

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Year:  2007        PMID: 17438245     DOI: 10.1001/archotol.133.4.327

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN: 0886-4470


  3 in total

1.  Scaffold-free tissue-engineered cartilage implants for laryngotracheal reconstruction.

Authors:  David A Gilpin; Mark S Weidenbecher; James E Dennis
Journal:  Laryngoscope       Date:  2010-03       Impact factor: 3.325

2.  The efficacy of slide tracheoplasty in a growing rabbit model.

Authors:  Yoichi Takano; Kosaku Maeda; Chieko Hisamatsu; Eiji Nishijima
Journal:  Pediatr Surg Int       Date:  2012-01       Impact factor: 1.827

3.  Successful Treatment of Tracheal Stenosis with Slide Tracheoplasty after the Failure of Resection with End-to-End Anastomosis.

Authors:  So-Yoon Lee; Sang Min Lee; Se-Ra Park; Jae-Won Chang; Tae-Sub Chung; Hong-Shik Choi
Journal:  Clin Exp Otorhinolaryngol       Date:  2009-12-31       Impact factor: 3.372

  3 in total

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