Literature DB >> 174381

Vascular and neuroglial changes in experimental herpes simplex encephalitis: ultrastructural study.

M L Arsénio-Nunes, I Cerutti, E Farkas-Bargeton.   

Abstract

Generalized vascular changes and diffused proliferation of reactive microglia were observed in an experimental model of HSV encephalitis of mice. The wide spread of these changes contrasted with the localized character of virus replication and the confined areas of damaged nervous tissue. The vascular and microglial changes were precocious in animals inoculated with concentrated virus suspension (10(5.5)LD50) while they appeared late in mice inoculated with diluted virus suspension (100 LD50). After inoculation with U.V. inactivated virus no changes were seen. The results obtained in this study suggest that the vascular and microglial modifications are not related to a direct cytopathic effect of the virus but dependent on the amount of virus present in the central nervous system and linked to the virus DNA.

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Year:  1975        PMID： 174381     DOI： 10.1007/bf00688397

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  27 in total

1.  Incorporation of thymidine-H3 by cells in normal and injured mouse spinal cord.

Authors:  E K ADRIAN; B E WALKER
Journal:  J Neuropathol Exp Neurol       Date:  1962-10       Impact factor: 3.685

2.  An ultrastructure study of herpes simplex virus encephalitis.

Authors:  F H Norris
Journal:  J Neuropathol Exp Neurol       Date:  1972-10       Impact factor: 3.685

3.  Cytochemical and ultrastructural studies of chromatolysis in neurones infected with Herpes simplex virus.

Authors:  K Kristensson; M Haltia
Journal:  Virchows Arch B Cell Pathol       Date:  1970

4.  Herpes simplex virus products in productive and abortive infection. II. Electron microscopic and immunological evidence for failure of virus envelopment as a cause of abortive infection.

Authors:  S B Spring; B Roizman; J Schwartz
Journal:  J Virol       Date:  1968-04       Impact factor: 5.103

5.  Electron microscopy of herpes simplex virus. I. Entry.

Authors:  C Morgan; H M Rose; B Mednis
Journal:  J Virol       Date:  1968-05       Impact factor: 5.103

6.  Electron microscopic observations on Herpesvirus hominis (herpes simplex virus) encephalitis in man.

Authors:  J L Swanson; J E Craighead; E S Reynolds
Journal:  Lab Invest       Date:  1966-12       Impact factor: 5.662

7.  Growth of herpes simplex virus in transformed glial and neuronal cells in tissue culture: ultrastructural studies.

Authors:  J Schwartz; T S Elizan
Journal:  J Neuropathol Exp Neurol       Date:  1973-04       Impact factor: 3.685

8.  [Glia in the hypoglossal nucleus of the rat following axotomy (author's transl)].

Authors:  M Davidoff
Journal:  Z Zellforsch Mikrosk Anat       Date:  1973-08-03

9.  Experimental herpes simplex encephalitis: early neuropathologic changes.

Authors:  J R Baringer; J F Griffith
Journal:  J Neuropathol Exp Neurol       Date:  1970-01       Impact factor: 3.685

10.  Herpes simplex virus-host cell relationships in organized cultures of mammalian nerve tissues.

Authors:  L A Feldman; R D Sheppard; M B Bornstein
Journal:  J Virol       Date:  1968-06       Impact factor: 5.103
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  8 in total

Review 1.  Viral diseases of the central nervous system.

Authors:  Phillip A Swanson; Dorian B McGavern
Journal:  Curr Opin Virol       Date:  2015-02-12       Impact factor: 7.090

2.  Proteomics analysis of HSV-1-induced alterations in mouse brain microvascular endothelial cells.

Authors:  Hui Liu; Chu-Xin Huang; Qiang He; Dong Li; Min-Hua Luo; Fei Zhao; Wei Lu
Journal:  J Neurovirol       Date:  2019-05-29       Impact factor: 2.643

3.  Vascular and neuroglial changes in experimental herpes simplex encephalitis enzyme histochemical study.

Authors:  E Farkas-Bargeton; M F Diebler; K Kristensson; E Lycke; P Sourander
Journal:  Acta Neuropathol       Date:  1975-10-27       Impact factor: 17.088

Review 4.  T Lymphocytes as Measurable Targets of Protection and Vaccination Against Viral Disorders.

Authors:  Anne Monette; Andrew J Mouland
Journal:  Int Rev Cell Mol Biol       Date:  2018-10-24       Impact factor: 6.813

5.  Mouse hydrocephalus and encephalitis following intracerebral infection with Newcastle disease vaccine viruses.

Authors:  M Chew-Lim; H E Webb
Journal:  Br J Exp Pathol       Date:  1976-08

6.  The alterations of matrix metalloproteinase-9 in mouse brainstem during herpes simplex virus type 1-induced facial palsy.

Authors:  Dong Chen; Daogong Zhang; Lei Xu; Yuechen Han; Haibo Wang
Journal:  J Mol Neurosci       Date:  2013-07-02       Impact factor: 3.444

7.  Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.

Authors:  Grégory Caignard; Gabriel A Leiva-Torres; Michael Leney-Greene; Benoit Charbonneau; Anne Dumaine; Nassima Fodil-Cornu; Michal Pyzik; Pablo Cingolani; Jeremy Schwartzentruber; Jeremy Dupaul-Chicoine; Huaijian Guo; Maya Saleh; André Veillette; Marc Lathrop; Mathieu Blanchette; Jacek Majewski; Angela Pearson; Silvia M Vidal
Journal:  PLoS Pathog       Date:  2013-09-12       Impact factor: 6.823

Review 8.  COVID-19 and Neurological Impairment: Hypothalamic Circuits and Beyond.

Authors:  Bashair M Mussa; Ankita Srivastava; Anthony J M Verberne
Journal:  Viruses       Date:  2021-03-17       Impact factor: 5.048
  8 in total

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