| Literature DB >> 17435140 |
Elain Fu1, Timothy Chinowsky, Kjell Nelson, Kyle Johnston, Thayne Edwards, Kristen Helton, Michael Grow, John W Miller, Paul Yager.
Abstract
Saliva is an underused fluid with considerable promise for biomedical testing. Its potential is particularly great for monitoring small-molecule analytes since these are often present in saliva at concentrations that correlate well with their free levels in blood. We describe the development of a prototype diagnostic device for the rapid detection of the antiepileptic drug (AED) phenytoin in saliva. The multicomponent system includes a hand-portable surface plasmon resonance (SPR) imaging instrument and a disposable microfluidic assay card.Entities:
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Year: 2007 PMID: 17435140 DOI: 10.1196/annals.1384.026
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN: 0077-8923 Impact factor: 5.691