| Literature DB >> 17434731 |
Ana B Bueno1, Jeremy Gilmore, John Boot, Richard Broadmore, Jane Cooper, Jeremy Findlay, Lorna Hayhurst, Alicia Marcos, Carlos Montero, Stephen Mitchell, Graham Timms, Rosemarie Tomlinson, Louise Wallace, Leslie Walton.
Abstract
SAR around a known molecule with dual 5-HT(1D) antagonist and 5-HT(transporter) inhibitory activity has led to the discovery of molecules with improved dual activity and reduced cross-reactivity toward other aminergic receptors (5-HT(1B), alpha(1), and D(2)).Entities:
Mesh：
Substances：
Year: 2007 PMID： 17434731 DOI： 10.1016/j.bmcl.2007.03.101
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823