| Literature DB >> 17433727 |
Abstract
Accumulating body of evidence reveals that hSIRT1, an NAD(+)-dependent protein deacetylase, is involved in regulating numerous biological processes. Therefore cellular functions of hSIRT1 are highly pleiotropic. The integrated hypothetical mechanisms of hSIRT1 action contributing to regulating cellular senescence and longevity have been proposed. Based on recent evidence, I propose that hSIRT1 is a potential biomarker for tumorigenesis.Entities:
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Year: 2006 PMID： 17433727 DOI： 10.1016/j.cellbi.2006.11.003
Source DB: PubMed Journal: Cell Biol Int ISSN： 1065-6995 Impact factor: 3.612