| Literature DB >> 17433709 |
Ya-Li Liu1, Hui Bi, Su-Min Chi, Rong Fan, Yue-Min Wang, Xin-Liang Ma, Yao-Ming Chen, Wen-Jing Luo, Jian-Ming Pei, Jing-Yuan Chen.
Abstract
The effect of compound nutrients on serum concentrations of the cytokines, such as interleukin (IL)-2, tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL)-6 in immobilization and cold water-immersion stressed rat were investigated. Oral (gavage) administration of compound nutrients was found to attenuate the acute and chronic immobilization and cold water-immersion stress-induced increase in serum IL-6 level and decrease in IL-2 level. Compound nutrients exerted different effects on TNF-alpha level in two different models studied, with reduced serum TNF-alpha level in acute stress, while no significant effect in chronic stress. These results suggested that compound nutrients might be proposed as a possible candidate in the research or therapeutic modulation of stress-related disorders.Entities:
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Year: 2007 PMID： 17433709 DOI： 10.1016/j.cyto.2007.02.009
Source DB: PubMed Journal: Cytokine ISSN： 1043-4666 Impact factor: 3.861