Literature DB >> 1743206

Excretion of gallium 67 in human breast milk and its inadvertent ingestion by a 9-month-old child.

S Rubow1, J Klopper, P Scholtz.   

Abstract

The concentration of radioactivity excreted in breast milk following the administration of gallium 67 to 3 patients was measured in milk samples obtained for several days after injection. Similar values were obtained from all 3 patients, with milk samples obtained approximately 120 h after administration containing 4.3-5.7 Bq/ml per MBq of 67Ga administered. These values are lower than those previously reported. The image of a child who had inadvertently been breast-fed for 48 h after administration of 67Ga to the mother showed activity in the intestines only. Our results seem to confirm recommendations by other authors that gallium scintigraphy should be avoided in nursing mothers. Should the administration of 67Ga be inevitable, breastfeeding should be discontinued, since interruption periods of approximately 2 weeks may be required to reduce the effective dose equivalent to the infant below 1 mSv. However, close contact between mother and child need not be avoided.

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Year:  1991        PMID: 1743206     DOI: 10.1007/bf00175063

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN: 0340-6997


  12 in total

1.  Excretion of iodine-123-hippuran, technetium-99m-red blood cells, and technetium-99m-macroaggregated albumin into breast milk.

Authors:  M R Rose; M C Prescott; K J Herman
Journal:  J Nucl Med       Date:  1990-06       Impact factor: 10.057

2.  67 Ga-accumulation in malignant tumors and in the prelactating or lactating breast.

Authors:  J Fogh; N A Thorn
Journal:  Proc Soc Exp Biol Med       Date:  1971-12

3.  Gallium 67 concentration in human breast milk.

Authors:  S M Larson; G L Schall
Journal:  JAMA       Date:  1971-10-11       Impact factor: 56.272

4.  Indium-111 radioactivity in breast milk.

Authors:  D Butt; K F Szaz
Journal:  Br J Radiol       Date:  1986-01       Impact factor: 3.039

5.  Uptake of 67Ga in the lactating breast and its persistence in milk: case report.

Authors:  R E Tobin; P B Schneider
Journal:  J Nucl Med       Date:  1976-12       Impact factor: 10.057

6.  Estimation of close contact doses to young infants from surface dose rates on radioactive adults.

Authors:  P J Mountford
Journal:  Nucl Med Commun       Date:  1987-11       Impact factor: 1.690

Review 7.  A review of the secretion of radioactivity in human breast milk: data, quantitative analysis and recommendations.

Authors:  P J Mountford; A J Coakley
Journal:  Nucl Med Commun       Date:  1989-01       Impact factor: 1.690

8.  Excretion of radionuclides in human breast milk after the administration of radiopharmaceuticals.

Authors:  L Ahlgren; S Ivarsson; L Johansson; S Mattsson; B Nosslin
Journal:  J Nucl Med       Date:  1985-09       Impact factor: 10.057

9.  Radionuclide administration to nursing mothers: mathematically derived guidelines.

Authors:  B M Romney; E L Nickoloff; P D Esser; P O Alderson
Journal:  Radiology       Date:  1986-08       Impact factor: 11.105

10.  Indium-111 in breast milk following administration of indium-111-labeled leukocytes.

Authors:  S R Hesslewood; J R Thornback; J M Brameld
Journal:  J Nucl Med       Date:  1988-07       Impact factor: 10.057

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