Literature DB >> 17431642

Orchidopexy and its impact on fertility.

Feilim Murphy1, Thambipillai Sri Paran, Prem Puri.   

Abstract

We critically analysed the factors known to influence the fertility potential after orchidopexy in children. A comprehensive literature review of all publications in the English language listed in Medline using the words cryptorchidism, undescended testis, orchidopexy, fertility, semen analysis and surgery from 1970 to 2005. In unilateral ectopic, canalicular and emergent testes, as long as the surgery is carried out in early childhood, fertility outcome is good (>90%). The majority of the bilateral abdominal testes are infertile. While unilateral abdominal testes and unilateral absent or vanishing testes have favourable fertility potential, quantification has proven difficult. Despite multiple studies, fertility in crypt orchid tests is still an uncertain issue. Hormonal treatment in conjunction with early surgical correction has not been fully explored. We recommend orchidopexy soon after 6-7 months of age, corrected for term, to maximise the future fertility potential.

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Year:  2007        PMID: 17431642     DOI: 10.1007/s00383-007-1900-3

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   2.003


  74 in total

Review 1.  Testicular descent and cryptorchidism: the state of the art in 2004.

Authors:  John M Hutson; Suzanne Hasthorpe
Journal:  J Pediatr Surg       Date:  2005-02       Impact factor: 2.545

2.  Conception rates and assisted reproduction in subfertility due to unilateral cryptorchidism.

Authors:  A M Mahmoud; F H Comhaire; D E Abdel-Rahim; K M Abdel-Hafez
Journal:  Andrologia       Date:  1996 May-Jun       Impact factor: 2.775

3.  Semen analysis of patients who had orchidopexy at or after seven years of age.

Authors:  P Puri; B O'Donnell
Journal:  Lancet       Date:  1988-11-05       Impact factor: 79.321

4.  Testicular microlithiasis and antisperm antibodies following testicular biopsy in boys with cryptorchidism.

Authors:  Rakesh P Patel; Thomas F Kolon; Dale S Huff; Michael C Carr; Stephen A Zderic; Douglas A Canning; Howard M Snyder
Journal:  J Urol       Date:  2005-11       Impact factor: 7.450

5.  Clinical, physical, sperm and hormonal data in 251 adults operated on for cryptorchidism in childhood.

Authors:  J Gracia; J Sánchez Zalabardo; J Sánchez García; C García; A Ferrández
Journal:  BJU Int       Date:  2000-06       Impact factor: 5.588

6.  What is the rate of spontaneous testicular descent in infants with cryptorchidism?

Authors:  David L Wenzler; David A Bloom; John M Park
Journal:  J Urol       Date:  2004-02       Impact factor: 7.450

7.  Significance of epididymal and ductal anomalies associated with undescended testis: study in 652 cases.

Authors:  M Mollaeian; V Mehrabi; B Elahi
Journal:  Urology       Date:  1994-06       Impact factor: 2.649

Review 8.  Undescended testis: the effect of treatment on subsequent risk of subfertility and malignancy.

Authors:  C Chilvers; N E Dudley; M H Gough; M B Jackson; M C Pike
Journal:  J Pediatr Surg       Date:  1986-08       Impact factor: 2.545

9.  The significance of postnatal gonadotropin surge for testicular development in normal and cryptorchid testes.

Authors:  F Hadziselimović; L Thommen; J Girard; B Herzog
Journal:  J Urol       Date:  1986-07       Impact factor: 7.450

10.  Malformations of the epididymis in undescended testis.

Authors:  W J Koff; R Scaletscky
Journal:  J Urol       Date:  1990-02       Impact factor: 7.450

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  19 in total

Review 1.  Ideal timing of orchiopexy: a systematic review.

Authors:  Emily Chan; Carolyn Wayne; Ahmed Nasr
Journal:  Pediatr Surg Int       Date:  2014-01       Impact factor: 1.827

2.  Undescended testis guideline - is it being implemented in practice?

Authors:  Kai O Hensel; Stefan Wirth
Journal:  Dtsch Arztebl Int       Date:  2014-09-26       Impact factor: 5.594

Review 3.  What is the ideal surgical approach for intra-abdominal testes? A systematic review.

Authors:  Carolyn Wayne; Emily Chan; Ahmed Nasr
Journal:  Pediatr Surg Int       Date:  2015-02-08       Impact factor: 1.827

Review 4.  Surgical approach to the palpable undescended testis.

Authors:  Reju J Thomas; Andrew J A Holland
Journal:  Pediatr Surg Int       Date:  2014-05-29       Impact factor: 1.827

Review 5.  Management of non-obstructive azoospermia.

Authors:  Koji Chiba; Noritoshi Enatsu; Masato Fujisawa
Journal:  Reprod Med Biol       Date:  2016-01-18

6.  Variations in timing of surgery among boys who underwent orchidopexy for cryptorchidism.

Authors:  Paul J Kokorowski; Jonathan C Routh; Dionne A Graham; Caleb P Nelson
Journal:  Pediatrics       Date:  2010-08-23       Impact factor: 7.124

7.  Enteric neuron density correlates with clinical features of severe gut dysmotility.

Authors:  Elisa Boschetti; Carolina Malagelada; Anna Accarino; Juan R Malagelada; Rosanna F Cogliandro; Alessandra Gori; Elena Bonora; Fiorella Giancola; Francesca Bianco; Vitaliano Tugnoli; Paolo Clavenzani; Fernando Azpiroz; Vincenzo Stanghellini; Catia Sternini; Roberto De Giorgio
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2019-09-23       Impact factor: 4.052

8.  The impact of simple orchiectomy on semen quality and endocrine parameters in postpubertal cryptorchid men.

Authors:  Hasan Cem Irkilata; Yusuf Kibar; Seref Basal; Bulent Kurt; Armagan Gunal; Bilal Fırat Alp; Ender Oral; Ugur Musabak; Lutfu Tahmaz; Murat Dayanc
Journal:  Int Urol Nephrol       Date:  2012-08-05       Impact factor: 2.370

9.  Awareness of Common Pediatric Surgical Entities among Practicing Indian Pediatricians.

Authors:  Santosh Kumar Mahalik; Akash Bihari Pati; Kanishka Das
Journal:  J Indian Assoc Pediatr Surg       Date:  2021-03-04

10.  Operative management of cryptorchidism: guidelines and reality--a 10-year observational analysis of 3587 cases.

Authors:  Kai O Hensel; Tawa Caspers; Andreas C Jenke; Ekkehard Schuler; Stefan Wirth
Journal:  BMC Pediatr       Date:  2015-09-10       Impact factor: 2.125

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