Literature DB >> 17430226

Artemisinin, promising lead natural product for various drug developments.

Seokjoon Lee1.   

Abstract

Artemisinin and its synthetic derivatives are widely used for antimalarial agents in the world. Moreover, they are discovered to additionally use as anticancer, antiangiogenesis, antiviral, immunosuppressive, and antifungal agents. Recent research results supported that it is a very promising field in drug discovery. In this review, it will discuss the structural and biological features of artemisinin and its derivatives that have published since 2003 except antimalarial, and show that they are useful lead compounds for novel drug discovery.

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Year:  2007        PMID： 17430226     DOI： 10.2174/138955707780363837

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  14 in total

Review 1.  Scalable biocatalytic C-H oxyfunctionalization reactions.

Authors:  Suman Chakrabarty; Ye Wang; Jonathan C Perkins; Alison R H Narayan
Journal:  Chem Soc Rev       Date:  2020-07-23       Impact factor: 54.564

2.  Dihydroartemisinin induces apoptosis of cervical cancer cells via upregulation of RKIP and downregulation of bcl-2.

Authors:  Chun-Jie Hu; Lei Zhou; Yan Cai
Journal:  Cancer Biol Ther       Date:  2013-12-11       Impact factor: 4.742

3.  Upregulation of the MCL-1S protein variant following dihydroartemisinin treatment induces apoptosis in cholangiocarcinoma cells.

Authors:  Hui Hu; Chunlu Tan; Xubao Liu; Feng Luo; Kezhou Li
Journal:  Oncol Lett       Date:  2015-09-29       Impact factor: 2.967

4.  Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers.

Authors:  Desmond Slade; Ahmed M Galal; Waseem Gul; Mohamed M Radwan; Safwat A Ahmed; Shabana I Khan; Babu L Tekwani; Melissa R Jacob; Samir A Ross; Mahmoud A Elsohly
Journal:  Bioorg Med Chem       Date:  2009-10-30       Impact factor: 3.641

5.  The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte.

Authors:  Ya He; Jinjin Fan; Haobo Lin; Xiuyan Yang; Yujin Ye; Liuqin Liang; Zhongping Zhan; Xiuqing Dong; Lin Sun; Hanshi Xu
Journal:  Rheumatol Int       Date:  2009-10-27       Impact factor: 2.631

6.  Dihydroartemisinin suppresses the proliferation of Epstein-Barr virus-associated gastric carcinoma cells via downregulation of latent membrane protein 2A.

Authors:  Wei Gong; Lei Zhang; Hui Yu; Qiang Yu; Wei-Kang Pan; Yin Wang; Xuan-Lin Wu; Qiang Liu
Journal:  Oncol Lett       Date:  2018-06-12       Impact factor: 2.967

7.  Methanol Extract of Artemisia apiacea Hance Attenuates the Expression of Inflammatory Mediators via NF- κ B Inactivation.

Authors:  Ji Choul Ryu; Sang Mi Park; Min Hwangbo; Sung Hui Byun; Sae Kwang Ku; Young Woo Kim; Sang Chan Kim; Seon Young Jee; Il Je Cho
Journal:  Evid Based Complement Alternat Med       Date:  2013-10-22       Impact factor: 2.629

Review 8.  Chikungunya virus (CHIKV) inhibitors from natural sources: a medicinal chemistry perspective.

Authors:  Soumendranath Bhakat; Mahmoud E S Soliman
Journal:  J Nat Med       Date:  2015-04-29       Impact factor: 2.343

9.  New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics.

Authors:  Si-Yuan Pan; Shu-Feng Zhou; Si-Hua Gao; Zhi-Ling Yu; Shuo-Feng Zhang; Min-Ke Tang; Jian-Ning Sun; Dik-Lung Ma; Yi-Fan Han; Wang-Fun Fong; Kam-Ming Ko
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-24       Impact factor: 2.629

10.  Chemical markers for the quality control of herbal medicines: an overview.

Authors:  Songlin Li; Quanbin Han; Chunfeng Qiao; Jingzheng Song; Chuen Lung Cheng; Hongxi Xu
Journal:  Chin Med       Date:  2008-06-28       Impact factor: 5.455
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