Literature DB >> 17428629

Anti-angiogenic activity of the methanol extract and its fractions of Ulmus davidiana var. japonica.

Hyun-Joo Jung1, Hye-Jin Jeon, Eun-Ju Lim, Eun-Kyoung Ahn, Yun Seon Song, Sanghyun Lee, Kuk Hyun Shin, Chang-Jin Lim, Eun-Hee Park.   

Abstract

This study aimed to elucidate anti-angiogenic activity of Ulmus davidiana var. japonica that has been widely used in folk medicine. The methanol extract (UDE) of Ulmus davidiana var. japonica concentration-dependently displayed a strong inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. The n-butanol fraction of UDE and subsequent 30% MeOH subfraction were identified to be most responsible for the anti-angiogenic activity.

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Year:  2007        PMID： 17428629     DOI： 10.1016/j.jep.2007.03.006

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  5 in total

1.  Vasorelaxing Activity of Ulmus davidiana Ethanol Extracts in Rats: Activation of Endothelial Nitric Oxide Synthase.

Authors:  Eun Jung Cho; Myoung Soo Park; Sahng Seop Kim; Gun Kang; Sunga Choi; Yoo Rhan Lee; Seok Jong Chang; Kwon Ho Lee; Sang Do Lee; Jin Bong Park; Byeong Hwa Jeon
Journal:  Korean J Physiol Pharmacol       Date:  2011-12-27       Impact factor: 2.016

2.  Ultrafine particles of Ulmus davidiana var. japonica induce apoptosis of gastric cancer cells via activation of caspase and endoplasmic reticulum stress.

Authors:  Joungjwa Ahn; Jong Suk Lee; Kyung Mi Yang
Journal:  Arch Pharm Res       Date:  2014-01-07       Impact factor: 4.946

Review 3.  The Chick Embryo Chorioallantoic Membrane as an In Vivo Assay to Study Antiangiogenesis.

Authors:  Domenico Ribatti
Journal:  Pharmaceuticals (Basel)       Date:  2010-03-08

4.  Ulmus davidiana ethanol extract inhibits monocyte adhesion to tumor necrosis factor-alpha-stimulated endothelial cells.

Authors:  Ki Mo Lee; Hee Kyoung Joo; Yu Ran Lee; Myoung Soo Park; Gun Kang; Sunga Choi; Kwon Ho Lee; Byeong Hwa Jeon
Journal:  Integr Med Res       Date:  2016-03-31

5.  A 60% Edible Ethanolic Extract of Ulmus davidiana Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis.

Authors:  Jeongho Park; Hyun-Ouk Kim; Kwang-Hyun Park; Myung-Bok Wie; Sun-Eun Choi; Jang-Hyuk Yun
Journal:  Molecules       Date:  2021-02-03       Impact factor: 4.411
  5 in total

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