Literature DB >> 17426943

[Doping. High-tech cheating in sport].

H Striegel1, P Simon.   

Abstract

Today, doping is no longer limited to the classical drugs with well known effects and side effects. Older generation anabolic steroids are used mainly in fitness and recreational sports. In contrast, due to doping tests, substances used in competitive sports include peptide hormones, medications not yet approved, and even specially developed drugs, such as designer steroids. Of the peptide hormones, particularly growth hormones (human growth hormone), erythropoietin and generics, insulin, and presumably insulin-like growth factor 1 are used. Substance groups potentially relevant for doping are selective androgen receptor modulators and gene therapy drugs. For most of these, there is no knowledge about side effects in healthy individuals, and no adequate doping tests. Therefore, anti-doping measures cannot rely solely on the continual improvement of doping analyses, but should include increased measures for doping prevention. Not only sports organizations, but also governmental agencies should be involved in developing and implementing these measures.

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Year:  2007        PMID: 17426943     DOI: 10.1007/s00108-007-1842-9

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  35 in total

Review 1.  Test method: GH.

Authors:  M Bidlingmaier; Z Wu; C J Strasburger
Journal:  Baillieres Best Pract Res Clin Endocrinol Metab       Date:  2000-03

2.  Clenbuterol and sport.

Authors:  A H Beckett
Journal:  Lancet       Date:  1992-11-07       Impact factor: 79.321

3.  Gene doping.

Authors:  H Lee Sweeney
Journal:  Sci Am       Date:  2004-07       Impact factor: 2.142

Review 4.  [Dangers and risks of black market anabolic steroid abuse in sports --gas chromatography-mass spectrometry analyses].

Authors:  M Ritsch; F Musshoff
Journal:  Sportverletz Sportschaden       Date:  2000-03       Impact factor: 1.077

5.  Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats.

Authors:  Jeffrey D Kearbey; Wenqing Gao; Ramesh Narayanan; Scott J Fisher; Di Wu; Duane D Miller; James T Dalton
Journal:  Pharm Res       Date:  2006-10-25       Impact factor: 4.200

Review 6.  Banned drugs in sport. Does the International Olympic Committee (IOC) list need updating?

Authors:  D R Mottram
Journal:  Sports Med       Date:  1999-01       Impact factor: 11.136

Review 7.  Effects of androgenic-anabolic steroids in athletes.

Authors:  Fred Hartgens; Harm Kuipers
Journal:  Sports Med       Date:  2004       Impact factor: 11.136

Review 8.  Differentiating factors between erythropoiesis-stimulating agents: a guide to selection for anaemia of chronic kidney disease.

Authors:  Robert Deicher; Walter H Hörl
Journal:  Drugs       Date:  2004       Impact factor: 9.546

9.  False-positive detection of recombinant human erythropoietin in urine following strenuous physical exercise.

Authors:  Monique Beullens; Joris R Delanghe; Mathieu Bollen
Journal:  Blood       Date:  2006-02-21       Impact factor: 22.113

Review 10.  Anabolic steroids and growth hormone.

Authors:  H A Haupt
Journal:  Am J Sports Med       Date:  1993 May-Jun       Impact factor: 6.202

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  1 in total

1.  A polymerase chain reaction-based methodology to detect gene doping.

Authors:  Adam Carter; Martin Flueck
Journal:  Eur J Appl Physiol       Date:  2011-08-17       Impact factor: 3.078

  1 in total

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