BACKGROUND: Hypodense fluorescein solution can be used intrathecally to facilitate and accelerate the identification of the fistulous site. METHODS: Eighteen patients were submitted for nasal endoscopic correction of rhinogenic cerebrospinal fluid fistulas after their identification with a hypodense sodium fluorescein solution. RESULTS: Intrathecal injection of hypodense fluorescein permitted a rapid and safe identification of the leak and did not present significant side effects. The fistulous site was identified in all patients, and the time needed for staining was <30 minutes in all cases. Surgery was successful in 88% of the patients after only one intervention, with the rate reaching 100% after a secondary intervention in cases of recurrence. CONCLUSION: Intrathecal injection of a hypodense sodium fluorescein solution permits a more precise, rapid, and safe endoscopic approach, with no need to place the patient in the Trendelenburg position or to wait for a long period of time before starting the surgical procedure.
BACKGROUND: Hypodense fluorescein solution can be used intrathecally to facilitate and accelerate the identification of the fistulous site. METHODS: Eighteen patients were submitted for nasal endoscopic correction of rhinogenic cerebrospinal fluid fistulas after their identification with a hypodense sodium fluorescein solution. RESULTS: Intrathecal injection of hypodense fluorescein permitted a rapid and safe identification of the leak and did not present significant side effects. The fistulous site was identified in all patients, and the time needed for staining was <30 minutes in all cases. Surgery was successful in 88% of the patients after only one intervention, with the rate reaching 100% after a secondary intervention in cases of recurrence. CONCLUSION: Intrathecal injection of a hypodense sodium fluorescein solution permits a more precise, rapid, and safe endoscopic approach, with no need to place the patient in the Trendelenburg position or to wait for a long period of time before starting the surgical procedure.
Authors: Michael Zhang; Tej D Azad; Harminder Singh; Smeer Salam; Saurabh Jain; Vijay K Anand; Theodore H Schwartz Journal: J Neurol Surg B Skull Base Date: 2018-04-13
Authors: Hussain Albaharna; Mohammad Alshareef; Saud Alromaih; Mohammad Aloulah; Saad Alsaleh; Ahmad Alroqi Journal: Turk Arch Otorhinolaryngol Date: 2021-10-15
Authors: Christine Steiert; Luisa M Kraus; Roland Roelz; Horst Urbach; Juergen Beck; Stephan Meckel; Juergen Grauvogel Journal: Biomed Res Int Date: 2022-04-29 Impact factor: 3.246
Authors: Manuel Bernal-Sprekelsen; Elena Rioja; Joaquim Enseñat; Karla Enriquez; Liza Viscovich; Freddy Enrique Agredo-Lemos; Isam Alobid Journal: Biomed Res Int Date: 2014-05-07 Impact factor: 3.411