An evaluation of vulvomucosal injections of prostaglandins for induction of parturition in swine.

Two trials were performed to evaluate the efficacy of prostaglandins administered via the vulvomucosal route at one-half the recommended dosage in comparison to prostaglandins injected intramuscularly (IM) at the standard dosage. In trial 1, sows on three commercial swine farms were given prostaglandin F2alpha at a dosage of 10 mg IM (n = 110) or 5 mg prostaglandin F2alpha using a vulvomucosal injection (n = 94). The numbers of sows farrowing within 36 h postinjection were 92 (84%) and 83 (88%), respectively. In trial 2, sows on four commercial swine operations were induced to farrow by means of one of three treatments: cloprostenol 175 mug IM (n = 71); cloprostenol 87.5 mug vulvomucosally (n = 57); or prostaglandin F2alpha 5 mg vulvomucosally (n = 96). The numbers of sows farrowing within 36 h postinduction were 69 (97%), 53 (93%), and 91 (94%), respectively.Vulvomucosal injections of prostaglandin F2alpha and cloprostenol at one-half the dosage appeared to be as effective as intramuscular injections of prostaglandin F2alpha and cloprostenol at the recommended level. There were fewer sows demonstrating restless behavior following the injection of lower dosages of prostaglandin F2alpha vulvomucosally, compared to sows given the recommended dosage of prostaglandin F2alpha IM.