Literature DB >> 17423507

Clinical and laboratory findings of a bleeding disorder in Simmental cattle.

G P Searcy, L Petrie.   

Abstract

Eight Simmental cattle were presented to the Western College of Veterinary Medicine over the past decade with historic or current prolonged episodes of bleeding. Spontaneous epistaxis, superficial hematomas, and prolonged bleeding following injury or minor surgery (such as tattooing) were frequent observations. Animals presented because of prolonged hemorrhage were anemic and debilitated. Compensatory erythropoiesis was compromised in these animals by depletion of iron stores due to chronic blood loss. Screening tests to assess coagulation were normal as were numbers and morphology of platelets. In vitro platelet aggregation was abnormal in all affected cattle. Three animals were euthanized due to uncontrollable hemorrhage but the precise source of hemorrhage was undetectable. These findings are consistent with bleeding due to a platelet function disorder which has been described previously in Simmental cattle.

Entities:  

Year:  1990        PMID: 17423507      PMCID: PMC1480644     

Source DB:  PubMed          Journal:  Can Vet J        ISSN: 0008-5286            Impact factor:   1.008


  2 in total

1.  Determination of serum iron and latent iron-binding capacity (LIBC).

Authors:  J P Persijn; W van der Slik; A Riethorst
Journal:  Clin Chim Acta       Date:  1971-11       Impact factor: 3.786

Review 2.  Assessment of bone marrow and body iron stores: old techniques and new technologies.

Authors:  G M Brittenham; E H Danish; J W Harris
Journal:  Semin Hematol       Date:  1981-07       Impact factor: 3.851

  2 in total
  4 in total

1.  A study of the inheritance of a bleeding disorder in Simmental cattle.

Authors:  R J Mapletoft; S M Schmutz; G P Searcy
Journal:  Can Vet J       Date:  2000-10       Impact factor: 1.008

2.  An inherited platelet function defect in a Simmental crossbred herd.

Authors:  P A Gentry; L A Cheryk; R D Shanks; R Healey
Journal:  Can J Vet Res       Date:  1997-04       Impact factor: 1.310

3.  Potential large animal models for gene therapy of human genetic diseases of immune and blood cell systems.

Authors:  Thomas R Bauer; Rima L Adler; Dennis D Hickstein
Journal:  ILAR J       Date:  2009

4.  Preliminary studies of a platelet function disorder in Simmental cattle.

Authors:  G P Searcy; D Sheridan; K A Dobson
Journal:  Can J Vet Res       Date:  1990-06       Impact factor: 1.310

  4 in total

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